ArticleAntioxidants (Basel, Switzerland)2025
Selenium Yeast Attenuated Lipopolysaccharide-Induced Inflammation in Porcine Mammary Epithelial Cells by Modulating MAPK and NF-κB Signaling Pathways.
Article in Antioxidants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Immunomodulatory and Anti-Inflammatory Effects of Phycocyanin Oligopeptide Combined with Selenium and Zinc in LPS-Induced Mice.Biomedicines · 2026Article
- Streptomyces thermolilacinus-mediated synthesis of Selenium Nanoparticles as biocompatible anti-inflammatory agent; characterization, radiolabeling, in vitro and in vivo evaluations.Folia microbiologica · 2026Article
- Harnessing the FOXO-SIRT1 axis: insights into cellular stress, metabolism, and aging.Biogerontology · 2025Review
- Mechanism of Huaiqihuang (HQH) against cyclophosphamide (CYP)-induced hippocampal neurotoxicity based on network pharmacology, molecular docking and experimental verification.Frontiers in cell and developmental biology · 2025Article
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Authors and funding
7 authors.
Funding
Abstract
Mastitis, a prevalent inflammatory disease in mammals, disrupts mammary gland function, compromises milk quality, and can contribute to increased offspring morbidity and mortality. Maintaining the health of porcine mammary epithelial cells (PMECs), the primary cell type in the mammary gland, is crucial for minimizing the adverse effects of this disease. Selenium yeast (SeY), an organic selenium compound known for its antioxidant and immune-enhancing properties, has yet to be fully understood in its role in modulating inflammation in mammary gland. In this study, lipopolysaccharide (LPS) (50 µg/mL, 24 h) significantly upregulated the expression of pro-inflammatory cytokines, including tumor necrosis factor-alpha (TNF-α), interleukin-6 (IL-6), interleukin-8 (IL-8), and interleukin-1β (IL-1β) (
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Registered trials
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