SynthesisEuropean child & adolescent psychiatry2025
Event-related potential in juvenile obsessive-compulsive disorder: a systematic review and meta-analysis of error- and correct-related negativity.
Synthesis in European child & adolescent psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Reaction Time Variability and Electrophysiological Indices of Performance Monitoring in Youths With Attention-Deficit/Hyperactivity Disorder and Obsessive-Compulsive Disorder.Psychophysiology · 2026Article
- Targeting self-reported and neural error sensitivity: Short- and long-term effects of a one-week online intervention.International journal of clinical and health psychology : IJCHPArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
The error-related negativity (ERN) is a negative wave observed in electroencephalography (EEG) following errors in certain neurocognitive tasks, such as the Flanker task. This wave has been found to be heightened in individuals suffering from obsessive-compulsive disorder (OCD) in several adult studies and meta-analyses. Therefore, the ERN may serve as a relevant neurobiological marker for OCD. However, the ERN exhibits some developmental aspects. Considering this, we conducted a meta-analysis of studies examining the ERN in children and adolescents with OCD. We identified nine studies that compared ERN amplitude during a Flanker task between youth with OCD and matched controls. Our meta-analysis revealed that ERN amplitude was elevated in juvenile OCD patients compared to controls. We did not find that age, task accuracy, or sex moderated the difference between patients and controls. In conclusion, our meta-analysis confirmed that the ERN observed during the Flanker task may be a relevant biological marker for OCD in children and adolescents.
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Registered trials
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