Evidence map›Paper›PMID 40227350›Full record

ArticleDie Naturwissenschaften2025

Exploring the potential of essential oils against airborne fungi from cultural heritage conservation premises.

Željko Savković, Ana Džamić, Jovana Veselinović, Milica Ljaljević Grbić, Miloš Stupar

Abstract read
PubMed Publisher
In one paragraph

Article in Die Naturwissenschaften, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. TiOMolecules (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Željko SavkovićFaculty of Biology, Institute of Botany and Botanical Garden "Jevremovac", University of Belgrade, Studentski Trg 16, 11000, Belgrade, Serbia. zsavkovic@bio.bg.ac.rs.ORCID http://orcid.org/0000-0002-6678-4958
Ana DžamićFaculty of Biology, Institute of Botany and Botanical Garden "Jevremovac", University of Belgrade, Studentski Trg 16, 11000, Belgrade, Serbia.
Jovana VeselinovićFaculty of Pharmacy Novi Sad, University Business Academy in Novi Sad, Heroja Pinkija 4, Novi Sad, Serbia.
Milica Ljaljević GrbićFaculty of Biology, Institute of Botany and Botanical Garden "Jevremovac", University of Belgrade, Studentski Trg 16, 11000, Belgrade, Serbia.
Miloš StuparFaculty of Biology, Institute of Botany and Botanical Garden "Jevremovac", University of Belgrade, Studentski Trg 16, 11000, Belgrade, Serbia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The activity of six essential oils was investigated against eight fungal isolates (four Aspergillus and four Penicillium species) isolated from cultural heritage conservation premises in Serbia. To analyze the chemical composition of essential oils (EOs), gas chromatography coupled with mass spectrometry was employed. The antifungal activity of selected EOs was investigated using microdilution and microatmosphere methods while the commercial biocide benzalkonium chloride (BAC) was used as a control. Furthermore, molecular docking was used as an efficacious in silico method for the determination of interaction between dominant EO compounds and enzyme CYP51, essential for fungal ergosterol synthesis. It was demonstrated that BAC, Cinnamomum zeylanicum, and Gaultheria procumbens EOs had the strongest antifungal activity, which is in concordance with the results of molecular docking. Namely, the highest energy of enzyme-cofactor interaction was obtained for eugenol (the dominant component of Syzygium aromaticum and C. zeylanicum EOs). Moreover, it was found that the most resistant fungal isolates were A. flavus and A. niger, while A. sydowii and P. citrinum were the most susceptible. The results of our study point to the possibility of using studied environmentally friendly biocides of biological origin for the preservation of historical monuments and artifacts.

Indexed as

Air MicrobiologyAntifungal AgentsFungiOils, VolatileAspergillusGas Chromatography-Mass SpectrometryMicrobial Sensitivity TestsMolecular Docking SimulationPenicilliumSerbiaAntifungal AgentsOils, VolatileAspergillus spp.BioactivityCultural heritageEssential oilsMolecular dockingPenicillium spp

Identifiers

PMID40227350

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.