Evidence map›Paper›PMID 40227333›Full record

ArticleAntioxidants (Basel, Switzerland)2025

Chaetocin, a Natural Inhibitor of Transketolase, Suppresses the Non-Oxidative Pentose Phosphate Pathway and Inhibits the Growth of Drug-Resistant Non-Small Cell Lung Cancer.

Song Li, Zhanying Lu, Wenli Jiang, Yao Xu, Ran Chen, Jie Wang, Binghua Jiao, Xiaoling Lu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Song LiDepartment of Biochemistry and Molecular Biology, Naval Medical University, Shanghai 200433, China.
Zhanying LuExperimental Training Center of Basic Medical Science, Naval Medical University, Shanghai 200433, China.
Wenli JiangDepartment of Biochemistry and Molecular Biology, Naval Medical University, Shanghai 200433, China.
Yao XuDepartment of Biochemistry and Molecular Biology, Naval Medical University, Shanghai 200433, China.
Ran ChenDepartment of Biochemistry and Molecular Biology, Naval Medical University, Shanghai 200433, China.
Jie WangDepartment of Biochemistry and Molecular Biology, Naval Medical University, Shanghai 200433, China.
Binghua JiaoDepartment of Biochemistry and Molecular Biology, Naval Medical University, Shanghai 200433, China.
Xiaoling LuDepartment of Biochemistry and Molecular Biology, Naval Medical University, Shanghai 200433, China.

Funding

National Natural Science Foundation of China 82373786Shanghai Sailing Program 22YF1458500
6 · The paper itself

Abstract

Worldwide, lung cancer is the most common cause of cancer-related death, which is made worse by the development of drug resistance during treatment. It is urgent to develop new therapeutic methods and small molecule drugs for tumor resistance. Chaetocin, extracted from

Indexed as

chaetocincisplatin resistancedrug targetnon-small cell lung cancertransketolase

Identifiers

PMID40227333
PMCPMC11939327

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.