Evidence map›Paper›PMID 40227315›Full record

ArticleAntioxidants (Basel, Switzerland)2025

Combining Abiotic Stresses as a Low-Cost Strategy for Increasing the Phenolic Content in Apple Agro-Industrial By-Products.

Esteban Villamil-Galindo, Daniel A Jacobo-Velázquez, Andrea Marcela Piagentini

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Esteban Villamil-GalindoInstituto de Tecnología de Alimentos, Facultad de Ingeniería Química, Universidad Nacional del Litoral, Santa Fe 3000, Argentina.ORCID 0000-0002-6316-8180
Daniel A Jacobo-VelázquezTecnologico de Monterrey, Escuela de Ingeniería y Ciencias, Av. General Ramón Corona 2514, Zapopan 45201, Mexico.ORCID 0000-0002-9478-2570
Andrea Marcela PiagentiniInstituto de Tecnología de Alimentos, Facultad de Ingeniería Química, Universidad Nacional del Litoral, Santa Fe 3000, Argentina.ORCID 0000-0002-0717-5503

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The circular economy approach offers innovative solutions for valorizing apple by-products through biofortification strategies transforming waste into high-value products and reducing environmental impact. This study evaluates innovative solutions for valorizing Granny Smith apple peel (RM) through biofortification in phenolic compounds using individual or combined abiotic stresses, like wounding stress and ultraviolet A (UVA) radiation. The effects of cutting type (Ct) [whole (C1), 5 mm (C2), 1.5 mm (C3)], storage temperature (ST) [20, 15, 10, 5 °C], and storage time (TM) [0, 12, 24, 48, 72 h] on phenylalanine ammonia-lyase (PAL) and polyphenol oxidase (PPO) activity, total phenolic content (TPC), and phenolic profiles were studied first. The results show that higher stress intensity (C3, 15 °C, 48 h) significantly enhanced secondary metabolism, leading to notable increases in PAL activity (1201%), PPO activity (308%), TPC levels (108-118%), and Procyanidin B2 (PACB2, 22%), the predominant phenolic compound. These changes were critical for improving the bioactive properties and antioxidant potential of RM. The second assay combined wounding stress (same levels of Ct and ST of previous assay, TM: 56 h) with UVA radiation (UVA-D) [0, 86.4 KJ m

Indexed as

biofortificationcircular economynatural antioxidantrevalorizationUV-A radiation

Identifiers

PMID40227315
PMCPMC11939634

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.