Evidence map›Paper›PMID 40227219›Full record

ArticleAntioxidants (Basel, Switzerland)2025

Natural Antioxidants Reduce Oxidative Stress and the Toxic Effects of RNA-CUG

Fernando Morales, Dayana Vargas, Melissa Palma-Jiménez, Esteban J Rodríguez, Gabriela Azofeifa, Oscar Hernández-Hernández

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Fernando MoralesInstituto de Investigaciones en Salud (INISA), Universidad de Costa Rica, San José 2060, Costa Rica.ORCID 0000-0002-6564-8671
Dayana VargasInstituto de Investigaciones en Salud (INISA), Universidad de Costa Rica, San José 2060, Costa Rica.
Melissa Palma-JiménezInstituto de Investigaciones en Salud (INISA), Universidad de Costa Rica, San José 2060, Costa Rica.ORCID 0000-0003-1986-0185
Esteban J RodríguezInstituto de Investigaciones en Salud (INISA), Universidad de Costa Rica, San José 2060, Costa Rica.ORCID 0000-0003-4628-139X
Gabriela AzofeifaDepartamento de Bioquímica, Escuela de Medicina, Universidad de Costa Rica, San José 2060, Costa Rica.ORCID 0000-0002-2484-9207
Oscar Hernández-HernándezLaboratorio de Medicina Genómica, Departamento de Genética, Instituto Nacional de Rehabilitación Luis Guillermo Ibarra Ibarra, INR-LGII, Mexico City 14389, Mexico.ORCID 0000-0001-6388-2459

Funding

The Marigold Foundation NAUniversidad de Costa Rica 742-B8-314
6 · The paper itself

Abstract

The toxic gain-of-function of RNA-CUG

Indexed as

antioxidantsglial cell modelinducible modelmyotonic dystrophyRNA toxic gain-of-functiontreatment

Identifiers

PMID40227219
PMCPMC11939792

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.