ArticleSchizophrenia bulletin2026
Insight and Its Trajectory: Predicting the Risk of Psychiatric Hospitalizations Among First-Episode Psychosis During the First Year of Coordinated Specialty Care.
Article in Schizophrenia bulletin, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- What happens after tapering off antipsychotics? Clinical trajectories of 267 first-episode patients who discontinued antipsychotic medication.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026Article
- Moments of Change in Group Psychotherapy: Exploring Therapeutic Factors and Relational Processes.Behavioral sciences (Basel, Switzerland) · 2026Article
- Early clinical insight in first-episode psychosis.Schizophrenia research. Cognition · 2026Article
- Examining sex as a potential moderator of metacognitive training for psychosis efficacy on cognitive insight and jumping to conclusions bias: Evidence from a large-scale harmonized database.Schizophrenia research. Cognition · 2026Article
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
backgroundThis study explored how baseline insight predicts psychiatric hospitalization risk among 186 individuals with first-episode psychosis in coordinated specialty care (CSC). We hypothesized that insight, a potentially modifiable factor, moderates the relationship between CSC enrollment and outcomes, with a high baseline and stable high insight predicting greater reductions in hospitalizations and lengths of stay (LOS).
designInsight was assessed using the G12 item of the positive and negative syndrome scale, categorizing participants into low (G12 ≥ 4; n = 87) or high (G12 < 4; n = 99) insight groups at baseline. Six longitudinal trajectories were identified: stable high (n = 48), increasing (n = 41), declining (n = 31), stable low (n = 27), high-low-high (n = 20), and low-high-low (n = 19). Hospitalization data were collected for 12 months pre- and post-CSC enrollment.
resultsParticipants with high baseline insight demonstrated a 95% greater relative reduction in hospitalizations (relative risk reduction = 1.95, P = .002), indicating that insight moderated the relationship between CSC enrollment and hospitalization outcomes. Longitudinally, the stable high insight group exhibited the most substantial reductions in hospitalizations (risk ratio [RR] = 0.12, P < .001) and LOS (RR = 0.04, P < .001), outperforming the stable low and fluctuating insight groups.
conclusionInsight moderates the relationship between CSC enrollment and hospitalization outcomes, predicting clinical improvements in early psychosis. Interventions targeting insight may enhance CSC benefits by reducing hospitalizations and improving recovery trajectories.
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