Evidence map›Paper›PMID 40227109›Full record

ArticleActa dermato-venereologica2025

Self-reported Nickel Allergy among Schoolchildren: Trends in Prevalence, Risk Factors, and Atopic Comorbidity.

Linnea Hedman, Malin Lindberg, Berndt Stenberg, Eva Rönmark, Maja Af Klinteberg

Abstract read
In one paragraph

Article in Acta dermato-venereologica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Linnea HedmanDepartment of Public Health and Clinical Medicine, The OLIN and Sunderby Research Unit, Umeå University, Umeå, Sweden.
Malin LindbergDepartment of Public Health and Clinical Medicine, Dermatology and Venereology, Umeå University, Umeå, Sweden.
Berndt StenbergDepartment of Public Health and Clinical Medicine, Dermatology and Venereology, Umeå University, Umeå, Sweden.
Eva RönmarkDepartment of Public Health and Clinical Medicine, The OLIN and Sunderby Research Unit, Umeå University, Umeå, Sweden.
Maja Af KlintebergDepartment of Public Health and Clinical Medicine, Dermatology and Venereology, Umeå University, Umeå, Sweden. maja.af.klinteberg@umu.se.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nickel allergy is common among children. The present study investigated prevalence trends of self-reported nickel allergy, risk factors, and atopic comorbidity among children. Eight-year-old children from Norrbotten County, Sweden, were recruited in 1996 (n = 3,430), 2006 (n = 2,585), and 2017 (n = 2,785). Self-reported nickel allergy decreased from 7.7% (2006) to 6.1% (2017; p = 0.024) and was significantly more common among girls. In 1996, only children with atopic dermatitis answered questions on nickel allergy. Among children with atopic dermatitis, no significant decrease was seen over the years 1996 to 2017. Ear piercing (odds ratio [OR] 1.93, 95% confidence interval [CI] 1.39-2.68 and OR 5.57, 95% CI 3.71-8.38) and female sex (OR 4.05, 95% CI 2.68-6.13 and OR 1.73, 95% CI 1.09-2.74) were risk factors for self-reported nickel allergy in 2006 and 2017, respectively. Self-reported nickel allergy was significantly more prevalent among children with atopic dermatitis than without in 2006 (12.3% vs 6.4%; p < 0.001) and 2017 (11.5% vs 5.1%; p < 0.001), and among children with allergic rhinitis in 2017 (8.6% vs 4.7%; p = 0.015). In conclusion, we found a decreasing prevalence of self-reported nickel allergy, but not among children with atopic dermatitis. Ear piercing and female sex were strongly associated with nickel allergy. Our findings also suggest that nickel allergy is associated with atopic dermatitis and allergic rhinitis.

Indexed as

Dermatitis, Allergic ContactDermatitis, AtopicNickelSelf ReportAge FactorsChildComorbidityFemaleHumansMaleOdds RatioPrevalenceRhinitis, AllergicRisk FactorsSex FactorsSwedenNickel

Identifiers

PMID40227109
PMCPMC12012752

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.