Evidence map›Paper›PMID 40226772›Full record

ArticleThe journal of allergy and clinical immunology. Global2025

A clinical continuum of aquagenic pruritus, aquadynia, and aquagenic urticaria responsive to β-blockers.

Evelien M Hutten, Inger F A Bocca-Tjeertes, Rick G Pleijhuis

Abstract readCase Reports
In one paragraph

Article in The journal of allergy and clinical immunology. Global, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Evelien M HuttenDepartment of Internal Medicine and Allergology, University Medical Center Groningen, Groningen, The Netherlands.
Inger F A Bocca-TjeertesDivision of Pediatric Pulmonology and Allergology, Beatrix Children's Hospital, University Medical Center Groningen, Groningen, The Netherlands.
Rick G PleijhuisDepartment of Internal Medicine and Allergology, University Medical Center Groningen, Groningen, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

β-Blockers have shown promising effects in preventing aquagenic pruritus, but they may also have a role in preventing aquagenic urticaria and aquadynia. The question arises as to whether aquagenic pruritus, aquadynia, and aquagenic urticaria should be considered distinct phenotypes or part of a disease continuum.

Indexed as

Adrenergic β-antagonistsantipruriticsaquadyniaaquagenic pruritusaquagenic urticariachronic inducible urticariaCINDUpropranololβ-blockers

Identifiers

PMID40226772
PMCPMC11986494

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.