Evidence map›Paper›PMID 40226633›Full record

ArticleJournal of tropical medicine2025

Vitamin D Deficiency is Associated With Dengue Severity in Pediatric Cases, Eastern India.

Sagnika Samal, Manoj Kumar Dash, Chinmay Kumar Behera, Gyanraj Singh, Mahesh Chandra Sahu, Biswadeep Das

Abstract read
In one paragraph

Article in Journal of tropical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sagnika SamalSchool of Biotechnology, KIIT-Deemed to be University, Bhubaneswar 751024, Odisha, India.ORCID https://orcid.org/0009-0009-7975-2224
Manoj Kumar DashSchool of Biotechnology, KIIT-Deemed to be University, Bhubaneswar 751024, Odisha, India.ORCID https://orcid.org/0009-0003-8303-0001
Chinmay Kumar BeheraDepartment of Pediatrics, Kalinga Institute of Medical Sciences, KIIT-Deemed to Be University, Bhubaneswar 751024, Odisha, India.
Gyanraj SinghDepartment of Anatomy, Jajati Keshari Medical College and Hospital, Jajpur 755001, Odisha, India.
Mahesh Chandra SahuICMR-Regional Medical Research Centre, Bhubaneswar 751023, Odisha, India.ORCID https://orcid.org/0000-0003-3736-2294
Biswadeep DasSchool of Biotechnology, KIIT-Deemed to be University, Bhubaneswar 751024, Odisha, India.ORCID https://orcid.org/0000-0001-8214-3600

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitamin D is an important modulator of host immune response during immunity development in context to several diseases in children. This study included 280 pediatric dengue cases, which were further stratified as dengue fever (DF), dengue with warning signs (DWS), and severe dengue (SD), wherein naturally circulating vitamin D metabolite, 25(OH)D was assessed, followed by statistical analysis for elucidating the role of serum 25(OH)D in dengue severity. qRT-PCR based serotyping showed that dengue virus (DENV)-2 was the major circulating DENV serotype in the patients. Among DENV cases, 92 (32.86%), 108 (38.57%), and 80 (28.57%) were diagnosed with DF, DWS, and SD, respectively. Among SD patients, serum 25(OH)D deficiency and insufficiency were observed in 37 (46.25%) and 43 (53.75%) patients, respectively, and found to be significantly associated with SD (

Indexed as

25(OH)D deficiencydengue feverdengue virusdengue with warning signssevere dengue

Identifiers

PMID40226633
PMCPMC11991798

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.