Evidence map›Paper›PMID 40226525›Full record

ArticleChina CDC weekly2025

Using Phylogenetic Analysis to Detect National and International Dimensions of Hepatitis C Virus 1b Transmission Clusters - China, 1989-2021.

He Jiang, Shujia Liang, Xiuling Wu, Jinghua Huang, Bo Li, Xuanhua Liu, Qin Meng, Shuai Tang, Qiuying Zhu, Guanghua Lan

Abstract read
In one paragraph

Article in China CDC weekly, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

He Jiang *Guangxi Key Laboratory of AIDS Prevention and Control and Achievement Transformation, Guangxi Center for Disease Prevention and Control, Nanning City, Guangxi Zhuang Autonomous Region, China.
Shujia Liang *Guangxi Key Laboratory for the Prevention and Control of Viral Hepatitis, Guangxi Center for Disease Prevention and Control, Nanning City, Guangxi Zhuang Autonomous Region, China.
Xiuling WuGuangxi Key Laboratory of AIDS Prevention and Control and Achievement Transformation, Guangxi Center for Disease Prevention and Control, Nanning City, Guangxi Zhuang Autonomous Region, China.
Jinghua HuangGuangxi Key Laboratory for Major Infectious Diseases Prevention and Control and Biosafety Emergency Response, Guangxi Center for Disease Prevention and Control, Nanning City, Guangxi Zhuang Autonomous Region, China.
Bo LiGuangxi Key Laboratory of AIDS Prevention and Control and Achievement Transformation, Guangxi Center for Disease Prevention and Control, Nanning City, Guangxi Zhuang Autonomous Region, China.
Xuanhua LiuGuangxi Key Laboratory for Major Infectious Diseases Prevention and Control and Biosafety Emergency Response, Guangxi Center for Disease Prevention and Control, Nanning City, Guangxi Zhuang Autonomous Region, China.
Qin MengGuangxi Key Laboratory of AIDS Prevention and Control and Achievement Transformation, Guangxi Center for Disease Prevention and Control, Nanning City, Guangxi Zhuang Autonomous Region, China.
Shuai TangGuangxi Key Laboratory for Major Infectious Diseases Prevention and Control and Biosafety Emergency Response, Guangxi Center for Disease Prevention and Control, Nanning City, Guangxi Zhuang Autonomous Region, China.
Qiuying ZhuGuangxi Key Laboratory for Major Infectious Diseases Prevention and Control and Biosafety Emergency Response, Guangxi Center for Disease Prevention and Control, Nanning City, Guangxi Zhuang Autonomous Region, China.
Guanghua LanGuangxi Key Laboratory of AIDS Prevention and Control and Achievement Transformation, Guangxi Center for Disease Prevention and Control, Nanning City, Guangxi Zhuang Autonomous Region, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

What is already known about this topic?: Phylogenetic analysis has revolutionized the detection and understanding of Hepatitis C Virus (HCV) transmission patterns. What is added by this report?: Three distinct transmission cluster patterns were identified across China: a large cluster with nationwide distribution, two medium clusters predominantly in the Central and Eastern China, and 103 small clusters scattered across 19 provincial-level administrative divisions (PLADs). Each cluster type exhibited unique characteristics of expansion risk and inter-provincial transmission patterns. No genetic linkages were found between Chinese sequences and those from other countries. What are the implications for public health practice?: These findings underscore the critical need for a comprehensive national molecular epidemiological surveillance network.

Indexed as

1b SubtypeHepatitis C VirusPhylogenetic AnalysisTransmission Clusters

Identifiers

PMID40226525
PMCPMC11986446

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.