Evidence map›Paper›PMID 40226405›Full record

ArticleJournal of tissue engineering and regenerative medicine2023

A Combinatorial Approach to Regenerate the Periodontal Ligament and Cementum in a Nondental Microenvironment.

Yongwen Guo, Mengting He, Peiqi Wang, Ding Bai, Jeong-Hui Park, Khandmaa Dashnyam, Jung-Hwan Lee, Olivier Huck, Nadia Benkirane-Jessel, Hae-Won Kim and 1 more

Abstract read
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In one paragraph

Article in Journal of tissue engineering and regenerative medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yongwen GuoState Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.ORCID 0000-0002-1122-7249
Mengting HeState Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.ORCID 0000-0001-7558-4475
Peiqi WangState Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.ORCID 0000-0001-8327-1700
Ding BaiState Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
Jeong-Hui ParkInstitute of Tissue Regeneration Engineering, Dankook University, Cheonan 31116, Republic of Korea.
Khandmaa DashnyamInstitute of Tissue Regeneration Engineering, Dankook University, Cheonan 31116, Republic of Korea.
Jung-Hwan LeeInstitute of Tissue Regeneration Engineering, Dankook University, Cheonan 31116, Republic of Korea.ORCID 0000-0001-8678-5459
Olivier HuckINSERM UMR 1260, Regenerative Nanomedicine, University of Strasbourg, Strasbourg 67084, France.
Nadia Benkirane-JesselINSERM UMR 1260, Regenerative Nanomedicine, University of Strasbourg, Strasbourg 67084, France.
Hae-Won KimInstitute of Tissue Regeneration Engineering, Dankook University, Cheonan 31116, Republic of Korea.ORCID 0000-0001-6400-6100
Murugan RamalingamIKERBASQUE, Basque Foundation for Science, Bilbao 48013, Spain.ORCID 0000-0001-6498-9792

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While treated dentin matrix (TDM) has been used for regeneration of dental tissues, the quality and quantity of regenerated periodontal tissue structure are suboptimal. The present study was undertaken to test whether the combined use of the TDM with dental follicle cells (DFCs) and Hertwig's epithelial root sheath (HERS) cells enhances the regeneration of periodontal structures in a nondental microenvironment. TDMs were fabricated from 3-month-old Sprague-Dawley (SD) rats. DFCs and HERS cells were isolated from postnatal 7-day SD rats. Purified DFCs and HERS cells, both in combination or alone, were seeded and cultured on TDM

Indexed as

Cellular MicroenvironmentDental CementumPeriodontal LigamentRegenerationAnimalsDental SacDentinRatsRats, Sprague-Dawley

Identifiers

PMID40226405
PMCPMC11919150

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.