Evidence map›Paper›PMID 40226397›Full record

SynthesisJournal of tissue engineering and regenerative medicine2023

3D Printing of Bone Substitutes Based on Vat Photopolymerization Processes: A Systematic Review.

Simon Enbergs, Jacob Spinnen, Tilo Dehne, Michael Sittinger

Abstract readSystematic Review
In one paragraph

Synthesis in Journal of tissue engineering and regenerative medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Simon EnbergsTissue Engineering Laboratory, BIH Center of Regenerative Therapies, Department of Rheumatology & Clinical Immunology, Charité-Universitätsmedizin Berlin, Charitéplatz 1, Berlin 10117, Germany.ORCID 0000-0003-3003-591X
Jacob SpinnenTissue Engineering Laboratory, BIH Center of Regenerative Therapies, Department of Rheumatology & Clinical Immunology, Charité-Universitätsmedizin Berlin, Charitéplatz 1, Berlin 10117, Germany.ORCID 0000-0002-6726-2860
Tilo DehneTissue Engineering Laboratory, BIH Center of Regenerative Therapies, Department of Rheumatology & Clinical Immunology, Charité-Universitätsmedizin Berlin, Charitéplatz 1, Berlin 10117, Germany.ORCID 0000-0001-8785-5869
Michael SittingerTissue Engineering Laboratory, BIH Center of Regenerative Therapies, Department of Rheumatology & Clinical Immunology, Charité-Universitätsmedizin Berlin, Charitéplatz 1, Berlin 10117, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Treatment options for critically sized bone defects are currently limited to metal osteosynthesis, autologous bone grafting, or calcium-based implants to bridge the gap. Additive manufacturing techniques pose a possible alternative. The light-basedthree-dimensional printing process of vat photopolymerization (VP) is of particular interest since it enables the printing of complex scaffold architectures at high resolution. This review compares multiple vat photopolymerization processes as well as the employed resin components' interactions with musculoskeletal cells and tissue. The results show an outstanding printing capability, exceeding the potential of other printing methods. However, despite the availability of various biocompatible materials, neither the mechanical strength of bone nor the scale necessary for clinical application has been achieved so far when relying on single material constructs. One possible solution is the development of adaptive hybrid constructs produced with multimaterial VP.

Indexed as

Bone SubstitutesPhotochemical ProcessesPolymerizationPrinting, Three-DimensionalAnimalsBiocompatible MaterialsHumansTissue EngineeringTissue ScaffoldsBiocompatible MaterialsBone Substitutes

Identifiers

PMID40226397
PMCPMC11918515

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.