ArticleJournal of biomedical optics2025
LED-based optoacoustic tomography of mice.
Article in Journal of biomedical optics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Efficient denoising in LED-based optoacoustic tomography with squeeze-and-excitation deep convolutional networks.Journal of biomedical optics · 2026Article
- Laser Ultrasound Super-Resolution Imaging for Multi-Parametric Non-Invasive Volumetric Characterization of Brain Cancer.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Performance characterization of light-emitting diode array-based photoacoustic computed tomography (LED-PACT).Biomedical optics express · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Significance: Optoacoustic tomography systems commonly employ bulky and expensive solid-state laser sources readily capable of generating dozens of millijoules of optical energy per pulse. Light-emitting diodes (LEDs) may offer a significantly more affordable and compact solution with excellent pulse-to-pulse stability. Yet, the optical design must optimize the energy density delivered to the target, given the relatively low per-pulse energy output of LEDs. Aim: We exploit a full-view LED-based optoacoustic tomography (FLOAT) configuration for Approach: The system features panoramic light illumination delivering 0.48 mJ of total per-pulse energy with an array of 160 LEDs stacked into a cylindrically focused circular ultrasound array transducer. Results: We characterize the imaging performance of the FLOAT system in tissue-mimicking phantoms, subsequently demonstrating its ability for Conclusions: It is anticipated that the compact, low-cost FLOAT imaging system will open up new venues in resource-limited settings for studying large-scale biodynamics such as pharmacokinetics and biodistribution of molecular agents and drugs on a whole-body level.
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Registered trials
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