ArticleClinical kidney journal2025
Renal functional reserve in living kidney donors.
Article in Clinical kidney journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
21 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Factors associated with renal functional reserve (RFR)-presence or absence-are not completely clear and remain underinvestigated. Methods: In this observational study, we evaluated the characteristics associated with the presence or absence of RFR in healthy subjects-living kidney donors-before donation. Renal function was assessed with measured glomerular filtration rate (GFR)-the clearance of iohexol-and RFR with the infusion of amino acids. An increase in GFR >10% after amino acid infusion indicated the presence of RFR. We defined Results: Subjects without RFR were predominantly women (81%) with the lowest body surface area (BSA; 1.71 ± 0.17 m Conclusions: The presence or absence of RFR was associated to differences in gender, weight, BMI, BSA and basal GFR. Women with small BSA may have lower GFR and no RFR, indicating possibly a lower renal endowment even in the normal range of renal function. The use of RFR may indicate a response to a higher metabolic demand in subjects with higher renal endowment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.