Evidence map›Paper›PMID 40226346›Full record

ReviewACS polymers Au2025

Cellulose-Based Nanofibers Infused with Biotherapeutics for Enhanced Wound-Healing Applications.

Deepanjan Datta, Sony Priyanka Bandi, Viola Colaco, Namdev Dhas, Suprio Shantanu Saha, Syed Zubair Hussain, Sudarshan Singh

Abstract readReview
In one paragraph

Review in ACS polymers Au, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Deepanjan DattaDepartment of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, Karnataka State 576104, India.ORCID https://orcid.org/0000-0001-8398-4276
Sony Priyanka BandiDepartment of Pharmacy, Birla Institute of Technology and Science (BITS) Pilani, Hyderabad Campus, Hyderabad, Telangana State 500078, India.
Viola ColacoDepartment of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, Karnataka State 576104, India.
Namdev DhasDepartment of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, Karnataka State 576104, India.
Suprio Shantanu SahaDepartment of Textile Engineering, Khulna University of Engineering and Technology, Khulna-9203, Khulna, Bangladesh.
Syed Zubair HussainDepartment of Textile Engineering, Khulna University of Engineering and Technology, Khulna-9203, Khulna, Bangladesh.
Sudarshan SinghFaculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID https://orcid.org/0000-0002-7929-3322

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanofibers fabricated from various materials such as polymers, carbon, and semiconductors have been widely used for wound healing and tissue engineering applications due to their excellent nontoxic, biocompatible, and biodegradable properties. Nanofibers with a diameter in the nanometer range possess a larger surface area per unit mass permitting easier addition of surface functionalities and release of biotherapeutics incorporated compared with conventional polymeric microfibers. Henceforth, nanofibers are a choice for fabricating scaffolds for the management of wound healing. Nanofibrous scaffolds have emerged as a promising method for fabricating wound dressings since they mimic the fibrous dermal extracellular matrix milieu that offers structural support for wound healing and functional signals for guiding tissue regeneration. Cellulose-based nanofibers have gained significant attention among researchers in the fabrication of on-site biodegradable scaffolds fortified with biotherapeutics in the management of wound healing. Cellulose is a linear, stereoregular insoluble polymer built from repeated units of d-glucopyranose linked with 1,4-β glycoside bonds with a complex and multilevel supramolecular architecture. Cellulose is a choice and has been used by various researchers due to its solubility in many solvents and its capacity for self-assembly into nanofibers, facilitating the mimicry of the natural extracellular matrix fibrous architecture and promoting substantial water retention. It is also abundant and demonstrates low immunogenicity in humans due to its nonanimal origins. To this end, cellulose-based nanofibers have been studied for protein delivery, antibacterial activity, and biosensor applications, among others. Taken together, this review delves into an update on cellulose-based nanofibers fused with bioactive compounds that have not been explored considerably in the past few years.

Identifiers

PMID40226346
PMCPMC11986729

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.