Evidence map›Paper›PMID 40226328›Full record

ArticleMolecular therapy. Nucleic acids2025

A Lyme disease mRNA vaccine targeting

Djamel Tahir, Virginie Geolier, Hugo Bruant, Anne Le Flèche-Matéos, Adeline Mallet, Marie Varloud, Céline Civat, Yves Girerd-Chambaz, Sandrine Montano, Corinne Pion and 3 more

Abstract read
In one paragraph

Article in Molecular therapy. Nucleic acids, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Djamel TahirInstitut Pasteur, Environnement et Risques Infectieux, Université Paris Cité, 75015 Paris, France.
Virginie GeolierInstitut Pasteur, Environnement et Risques Infectieux, Université Paris Cité, 75015 Paris, France.
Hugo BruantInstitut Pasteur, Environnement et Risques Infectieux, Université Paris Cité, 75015 Paris, France.
Anne Le Flèche-MatéosInstitut Pasteur, Environnement et Risques Infectieux, Université Paris Cité, 75015 Paris, France.
Adeline MalletInstitut Pasteur, Ultrastructural Bio-Imaging Core Facility, 75015 Paris, France.
Marie VarloudCeva Santé Animale, 10 Avenue de la Ballastière, 33500 Libourne, France.
Céline CivatSanofi Vaccines R&D, Campus Mérieux, 69280 Marcy l'Etoile, France.
Yves Girerd-ChambazSanofi Vaccines R&D, Campus Mérieux, 69280 Marcy l'Etoile, France.
Sandrine MontanoSanofi Vaccines R&D, Campus Mérieux, 69280 Marcy l'Etoile, France.
Corinne PionSanofi Vaccines R&D, Campus Mérieux, 69280 Marcy l'Etoile, France.
Elisabeth FerquelInstitut Pasteur, Environnement et Risques Infectieux, Université Paris Cité, 75015 Paris, France.
Vincent PavotSanofi Vaccines R&D, Campus Mérieux, 69280 Marcy l'Etoile, France.
Valérie ChoumetInstitut Pasteur, Environnement et Risques Infectieux, Université Paris Cité, 75015 Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lyme borreliosis (LB), caused by

Indexed as

Borrelia burgdorferiimmunogenicityLyme borreliosismRNA vaccinesMT: Oligonucleotides: Therapies and ApplicationsOspAouter surface protein Atick-borne pathogensticksvector-borne disease control

Identifiers

PMID40226328
PMCPMC11986965

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.