ArticleInfectious diseases & clinical microbiology2025
Frequency and Genotype Diversity of Human Pegiviruses (HPgV) in People Infected with Human Immunodeficiency Virus (HIV).
Article in Infectious diseases & clinical microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: Human pegiviruses (HPgV) belong to the Materials and Methods: The study analyzed plasma samples of HIV-infected, antiretroviral therapy-naive patients and control serum samples. HPgV RNA in the samples was investigated using the RT-nested PCR method, and primer sets designed from the 5'UTR region were used for amplification and genotyping using Sanger sequencing. Results: A total of 117 plasma samples from HIV-infected, antiretroviral therapy-naive patients and 100 control serum samples were included in the study. HPgV-1 RNA was detected in 24.78% of the patient group and 18% of the control group ( Conclusion: Genotype 2a was identified as the dominant genotype, and this finding is consistent with previous studies reported from Türkiye and other countries in the same geographical region. Further studies are needed to understand better the effects of the HPgV-1 virus on HIV infection.
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