Evidence map›Paper›PMID 40226240›Full record

ArticleIndian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India2025

Efficacy of Psyllium Husk as an Adjunct to PPI in Treating Laryngopharyngeal Reflux: A Clinical Perspective.

Amit Kumar Rana, Rohit Sharma, Mamta Verma, Abhay Deep Singh, Ashish Mehrotra

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Article in Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

5 authors.

Amit Kumar RanaDepartment of Otorhinolaryngology and Head Neck Surgery, Shri Ram Murti Smarak Institute of Medical Sciences Bareilly, Bareilly, UP India.ORCID 0000-0001-8196-5346
Rohit SharmaDepartment of Otorhinolaryngology and Head Neck Surgery, Shri Ram Murti Smarak Institute of Medical Sciences Bareilly, Bareilly, UP India.
Mamta VermaDepartment of Otorhinolaryngology and Head Neck Surgery, Shri Ram Murti Smarak Institute of Medical Sciences Bareilly, Bareilly, UP India.
Abhay Deep SinghDepartment of Otorhinolaryngology and Head Neck Surgery, Shri Ram Murti Smarak Institute of Medical Sciences Bareilly, Bareilly, UP India.
Ashish MehrotraDepartment of Otorhinolaryngology and Head Neck Surgery, Shri Ram Murti Smarak Institute of Medical Sciences Bareilly, Bareilly, UP India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Laryngopharyngeal reflux (LPR) is characterized by the retrograde flow of gastric contents into the laryngopharyngeal region, causing inflammation and nonspecific symptoms such as chronic cough, throat irritation, and hoarseness. Proton pump inhibitors (PPIs) are commonly used for treatment. This study evaluates the efficacy of psyllium husk as an adjunct to PPI therapy in managing LPR. A prospective study involving 505 patients with confirmed LPR was conducted. Patients were randomized into three treatment groups: PPI monotherapy, PPI combined with prokinetics, and PPI combined with psyllium husk. Outcomes were assessed using the Reflux Symptom Index (RSI), Reflux Finding Score (RFS), and patient adherence rates over 16 weeks. Statistical analysis included ANOVA and chi-square tests. The PPI-psyllium husk group demonstrated the highest symptom resolution rate of 82%, significantly greater than the 75% achieved by the PPI-prokinetic group and 65% by the PPI monotherapy group (

Indexed as

Chronic throat symptomsProkinetic agentsProton pump inhibitorsPsyllium husk therapyReflux finding scoreReflux symptom index

Identifiers

PMID40226240
PMCPMC11985717

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.