ArticleHealth science reports2025
A Comparative Study of Pancreatic Acinar Cell Carcinoma: A Case-Control Study.
Article in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Large pancreatic acinar cell carcinoma mass excision.Journal of surgical case reports · 2026Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Aims: Pancreatic acinar cell carcinoma (PACC) is rare. This study aims to elucidate its clinical features and survival outcomes. Methods: Patients diagnosed with PACC were enrolled. A comparison between PACC and pancreatic ductal adenocarcinoma (PDAC) patients was conducted following propensity score matching (PSM). Results: There were 11 resectable and nine unresectable PACC. The majority (60%) of PACC cases were located in the pancreatic head, with a median tumor size of 5.9 cm. Elevated serum lipase level was observed in 64.3% of cases. Regional lymph node involvement was found in 65.0%. The median survival was 20.0 months for resectable PACC patients compared to 6.7 months for unresectable cases. The 1-, 3-, and 5-year survival rates were 100%, 49.1%, and 32.0%, respectively, for resectable PACC patients, while for unresectable cases, they were 33.3%, 0%, and 0%. Resectable PACC patients exhibited lower rates of lymph node involvement (36.4% vs. 66.1%), lymphovascular invasion (LVI), 36.4% versus 72.8%, and perineural invasion (PNI), 45.5% versus 86.0%, compared to PDAC. Following PSM, there was no significant difference in survival between resectable PACC and PDAC. Conclusion: PACC is associated with lower rates of lymph node involvement, LVI, and PNI, which might attribute to superior outcome when compared with PDAC reported in the literature. However, there is no survival difference between resecrable PACC and PDAC after PSM.
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