Evidence map›Paper›PMID 40226138›Full record

ArticleIJTLD open2025

New drugs are not enough: addressing social determinants as a critical component of drug-resistant TB care.

D Giovenco, N S Shah, K Ansorge, D Operario, N R Gandhi

Abstract readEditorial
In one paragraph

Article in IJTLD open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

D GiovencoEmory University, Rollins School of Public Health, Atlanta, GA, USA.
N S ShahEmory University, Rollins School of Public Health, Atlanta, GA, USA.
K AnsorgeEmory University, Rollins School of Public Health, Atlanta, GA, USA.
D OperarioEmory University, Rollins School of Public Health, Atlanta, GA, USA.
N R GandhiEmory University, Rollins School of Public Health, Atlanta, GA, USA.

Funding

Emory/Georgia TB Research Advancement Center (TRAC)P30AI168386 · NIAID · EMORY UNIVERSITY · PI Jeffrey M Collins · 2022 to 2026
$5.8M
NIAID NIH HHS P30 AI168386
6 · The paper itself

Abstract

The global fight against drug-resistant TB (DR-TB) is hindered by an underappreciation of the importance of the social determinants of TB. Although shorter, all-oral regimens have improved treatment options, high rates of non-adherence persist due to stigma, financial hardship and other healthcare access barriers. Lessons from HIV highlight the importance of addressing structural and psychosocial factors in treatment management. Consideration of an ecosocial framework integrating biological, social and environmental perspectives is critical for effective DR-TB interventions. A paradigm shift toward patient-centered care and social support strategies is urgently needed to improve treatment outcomes and advance global efforts to eradicate DR-TB.

Indexed as

DR-TBperson-centered caresocial determinants of healthsocial epidemiology

Identifiers

PMID40226138
PMCPMC11984526

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.