Evidence map›Paper›PMID 40226093›Full record

ArticleScience and technology of advanced materials2025

NO tablet: autonomous generation of therapeutic nitric oxide in air through redox-promoted CO

Shinsuke Ishihara, Jan Labuta, Jonathan P Hill, Takashi Nakanishi, Manabu Kakinohana, Nobuo Iyi

Abstract read
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In one paragraph

Article in Science and technology of advanced materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shinsuke IshiharaResearch Center for Materials Nanoarchitectonics (MANA), National Institute for Materials Science (NIMS), Ibaraki, Japan.ORCID https://orcid.org/0000-0001-6854-6032
Jan LabutaResearch Center for Materials Nanoarchitectonics (MANA), National Institute for Materials Science (NIMS), Ibaraki, Japan.ORCID https://orcid.org/0000-0002-8329-0634
Jonathan P HillResearch Center for Materials Nanoarchitectonics (MANA), National Institute for Materials Science (NIMS), Ibaraki, Japan.ORCID https://orcid.org/0000-0002-4229-5842
Takashi NakanishiResearch Center for Materials Nanoarchitectonics (MANA), National Institute for Materials Science (NIMS), Ibaraki, Japan.ORCID https://orcid.org/0000-0002-8744-782X
Manabu KakinohanaDepartment of Anesthesiology, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan.
Nobuo IyiResearch Center for Materials Nanoarchitectonics (MANA), National Institute for Materials Science (NIMS), Ibaraki, Japan.ORCID https://orcid.org/0000-0001-5547-7031

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inhaled nitric oxide (iNO) is a powerful therapy for the treatment of various cardiopulmonary and respiratory diseases. However, access to iNO therapy is often limited by the necessity of cumbersome gas tanks and/or elaborate gas blending apparatus. Here, we report a lightweight, inexpensive, and maintenance-free tablet that autonomously generates a therapeutic quantity of NO in air. The tablet is composed of a thimble filter paper containing a powdery mixture of nitrite (NO

Indexed as

CO2 adsorptioncritical careequilibrium shiftlayered double hydroxidemedical deviceNitric oxide

Identifiers

PMID40226093
PMCPMC11986858

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.