ArticleJournal of bone oncology2025
Health- related quality of life after surgery for spinal metastases.
Article in Journal of bone oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Stereotactic body radiation therapy in elderly patients with spinal metastases.Journal of neuro-oncology · 2026Article
- Carbon fiber-reinforced peek versus titanium implants for the surgical treatment of spinal metastases: Evaluation of local disease control and quality of life.Journal of bone oncology · 2026Article
- Predictors of survival and functional outcomes after spinal surgery for multiple myeloma: a nationwide study of 200 patients.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Evolution of Surgical Outcomes in Spinal Metastases from Solid Tumors: A Comparative Analysis over 2 Decades.Revista brasileira de ortopedia · 2026Article
- [Evolution of Surgical Outcomes in Spinal Metastases from Solid Tumors: A Comparative Analysis over 2 Decades].Revista brasileira de ortopedia · 2026Article
- Prospective external validation of a three-predictor frailty model for 90-day survival and complications following spinal metastasis surgery.Journal of bone oncology · 2026Article
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Authors and funding
15 authors.
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Abstract
Background: Surgery for spinal metastases is almost always palliative and part of a multidisciplinary approach that has determined a significant increase of life expectancy in the last decade; thus, an improvement in health-related quality of life (HRQOL) is the main goal of the treatment of spinal metastases. We report here the results of a prospective study conducted with the aim of evaluating the impact of spinal surgery on HRQOL, measured by Patient-Reported Outcomes Measures (PROMs). We analyzed clinical outcomes (ambulatory status, performance status, pain, neurological status) and HRQOL scores (VAS, EQ5D, SF36) during the follow-up period and focused on factors that could affect quality of life, considering both psychological and physical issues. Methods: 169 patients (96 males, 73 females) with vertebral metastases who underwent surgery at a tertiary referral center were consecutively enrolled from August 2018 to October 2022. Clinical and surgical data were prospectively collected, and PROMs (VAS, EQ-5D and SF-36) were registered before surgery and during follow up. Results: The overall survival was 22 months, and a 61 % survival rate was registered at 1 year follow-up. We observed a significant improvement in walking ability, general performance status, pain and HRQOL after surgery, which was maintained during the follow up. Multivariate analysis identified three independent variables, capable of influencing the trend of HRQOL after surgery: the presence of pathological fracture, the preoperative neurological status and the local recurrence of disease. Discussion: This study confirms the effectiveness of surgery for spinal metastases in improving patients' performance status and demonstrates an overall improvement in HRQOL, which is maintained over time.
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