Evidence map›Paper›PMID 40225988›Full record

ArticleAmerican journal of translational research2025

Effects of labetalol plus magnesium sulfate on brain symptoms and pregnancy outcomes in hypertensive disorders of pregnancy.

Xiaolan Zhuang, Xingxing Li, Shikai Yu, Lin Zeng, Yuping Xu, Tingting Hu, Sailong Wan

Abstract read
In one paragraph

Article in American journal of translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiaolan ZhuangDepartment of Obstetrics and Gynecology, Ji'an Central People's Hospital Ji'an 343000, Jiangxi, China.
Xingxing LiDepartment of Obstetrics and Gynecology, Ji'an Central People's Hospital Ji'an 343000, Jiangxi, China.
Shikai YuDepartment of Critical Care Medicine, 908th Hospital of the Joint Logistics Support Force of The Chinese People's Liberation Army Nanchang 330000, Jiangxi, China.
Lin ZengDepartment of Neurosurgery, Fuzhou First People's Hospital Fuzhou 344000, Jiangxi, China.
Yuping XuDepartment of Neurosurgery, Fuzhou First People's Hospital Fuzhou 344000, Jiangxi, China.
Tingting HuDepartment of General Medicine, Fuzhou First People's Hospital Fuzhou 344000, Jiangxi, China.
Sailong WanDepartment of Neurosurgery, Fuzhou First People's Hospital Fuzhou 344000, Jiangxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to evaluate the clinical efficacy of labetalol (LBT) combined with magnesium sulfate (MgSO

methodsA total of 122 HDP patients admitted between January 2020 and June 2024 were included. Among them, 56 patients (control group) received MgSO

resultsThe research group demonstrated significantly better outcomes than the control group, including a higher overall therapeutic effectiveness rate, faster resolution of edema, hypertension, and proteinuria, a lower incidence of adverse pregnancy events, and more pronounced reductions in SBP, DBP, S/D, PI, and hs-CRP levels after treatment (all P < 0.05).

conclusionThe combination of LBT and MgSO

Indexed as

brain symptomshypertensive disorders of pregnancyLabetalolmagnesium sulfatepregnancy outcomes

Identifiers

PMID40225988
PMCPMC11982851

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.