Evidence map›Paper›PMID 40225982›Full record

ArticleAmerican journal of translational research2025

Clinical investigation of extracorporeal shock wave therapy combined with kinesitherapy on the treatment of delayed union of tibia and fibula fractures.

Qing Yang, Feng Xu, Jing Zhu, Li Sun, Qingming Qu, Su Liu, Siye Wang

Abstract read
In one paragraph

Article in American journal of translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Extracorporeal shockwave therapy in bone fractures: a systematic review.Archives of orthopaedic and trauma surgery · 2026
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qing YangDepartment of Rehabilitation Medicine, Affiliated Hospital of Nantong University Nantong 226001, Jiangsu, China.
Feng XuDepartment of Nephrology, The Second People's Hospital of Nantong Nantong 226001, Jiangsu, China.
Jing ZhuDepartment of Rehabilitation Medicine, Affiliated Hospital of Nantong University Nantong 226001, Jiangsu, China.
Li SunDepartment of Rehabilitation Medicine, Affiliated Hospital of Nantong University Nantong 226001, Jiangsu, China.
Qingming QuDepartment of Rehabilitation Medicine, Affiliated Hospital of Nantong University Nantong 226001, Jiangsu, China.
Su LiuDepartment of Rehabilitation Medicine, Affiliated Hospital of Nantong University Nantong 226001, Jiangsu, China.
Siye WangDepartment of Rehabilitation Medicine, Affiliated Hospital of Nantong University Nantong 226001, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the therapeutic efficacy of extracorporeal shock wave therapy (ESWT) combined with kinesitherapy (KT) for the treatment of delayed union of tibia and fibula fractures.

methodsA total of 68 patients with delayed healing of tibiofibular fractures were enrolled. These patients were divided into three groups: control, ESWT, and ESWT+KT. All patients underwent standard surgical treatment following the fracture. Patients in the ESWT group received shockwave therapy twice a week for 4 months, while those in the ESWT+KT group received additional exercise therapy twice a week over the same duration. The control group did not receive any specific intervention during this period. The pain levels of patients in all three groups were assessed using the Numerical Rating Scale (NRS) before and after treatment. Bone repair and callus formation were evaluated using the Lane-Sandhu and Fernandez-Esteve X-ray grading scales before and after treatment. Additionally, walking ability was assessed using the Functional Ambulation Classification (FAC), Hoffer walking ability grade, and Holden walking ability grade before and after treatment.

resultsNo significant differences were observed in patient baseline characteristics across the three groups (

conclusionESWT can enhance the walking function in patients with delayed union of tibia and fibula fractures. ESWT combined with KT demonstrates superior efficacy compared to monotherapy, as it not only improves walking function but also promotes bone healing.

Indexed as

Delayed healingextracorporeal shock wave therapyfractureskinesitherapy

Identifiers

PMID40225982
PMCPMC11982830

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.