Evidence map›Paper›PMID 40225844›Full record

ArticleFrontiers in psychiatry2025

The applicability and effectiveness of the cognitive behavioral therapy for insomnia (Smart CBT-I plus) online program in patients with insomnia disorder combined with anxiety and depression: a randomized controlled trial protocol.

Yating Zhao, Fangmei Ge, Xin Luo, Jingru Li, Jing Zhang, Yi Ju, Jie Zhang, Yong Wang, Dongbin Lyu, Yiren Qiu and 1 more

Abstract read
In one paragraph

Article in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yating ZhaoShanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Fangmei GeShanghai Putuo Mental Health Center, Shanghai, China.
Xin LuoShanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jingru LiShanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jing ZhangShanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yi JuShanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jie ZhangShanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yong WangShanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Dongbin LyuShanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yiren QiuShanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Chengmei YuanShanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Insomnia is often accompanied by depression and anxiety, which can seriously affect people's quality of life. Cognitive behavioral therapy for insomnia (CBT-I) is the first-line treatment, but the existing CBT-I ignores the intervention for anxiety-depressive symptoms, and has poor efficacy due to the lack of artificial support, poor compliance, the inability to spread widely and high dropping rate. A balance is needed between the convenience and efficiency of web-based technology and patient needs. Again in this context, an online WeChat applet (Smart CBT-I plus) will be developed with CBT-I technology as the core, integrating cognitive behavioral intervention modules for depression and anxiety. Objectives: This study will validate the effectiveness and applicability of Smart CBT-I plus by examining whether the Smart CBT-I plus study group will significantly reduce the distress of people suffering from insomnia with anxiety and/or depression symptoms compared to the psychoeducational group. Methods: In this parallel-group, randomized controlled trial, 180 patients seeking help for insomnia combined with anxiety and/or depression will be recruited, and they will be randomized with 60 patients being assigned to the psychoeducation group (control group), and 120 patients being assigned to the Smart CBT-I plus group (study group). Measurements will be taken at baseline, post-intervention, 6 and 12 month follow-up, at the same time, semi-structured qualitative interviews about the experience of using Smart CBT-I plus will be conducted with randomly selected patients from the study group. Results: The results will involve insomnia, depression and anxiety to explore its effectiveness, in-treatment dropout rates and subjective patient feedback to explore the applicability of Smart CBT-I plus. Future recommendations: Self-help platforms need to be more individually designed to reach a wider audience. Research aimed at a wider audience, such as the general public, will make the research more universal and the platform more meaningful.

Indexed as

cognitive behavioral treatment of insomniaeffectiveness and applicabilityinsomnia comorbidities anxiety and/or depressiononline self-help interventionprotocolrandomized controlled trial

Identifiers

PMID40225844
PMCPMC11986715

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.