Evidence map›Paper›PMID 40225795›Full record

ArticleAsian bioethics review2025

Ethical Dilemmas in Newborn Infants with Hypoxic Ischemic Encephalopathy.

Vijay R Baral, Yinru Lim, Priyantha Edison, Jerry Alan Menikoff

Abstract read
In one paragraph

Article in Asian bioethics review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Vijay R BaralDepartment of Neonatal and Developmental Medicine, Singapore General Hospital, Singapore.ORCID 0000-0001-9098-9083
Yinru LimDepartment of Neonatal and Developmental Medicine, Singapore General Hospital, Singapore.
Priyantha EdisonDepartment of Neonatal and Developmental Medicine, Singapore General Hospital, Singapore.
Jerry Alan MenikoffCentre for Biomedical Ethics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ethical conundrums are common in neonatal medicine, particularly around continuing or withdrawing intensive treatment in a critically ill baby. A common scenario is a baby born with compromised oxygen delivery around the time of birth (perinatal asphyxia) leading to a condition named hypoxic ischemic encephalopathy (HIE) which can have a high probability of death or long-term neurologic disability. This article reviews the key ethical dilemmas that underpin the clinical management of babies with severe HIE. The discussions, however, could be relevant in any newborn with a life-threatening illness where withdrawal or redirection of intensive treatment is being considered.

Indexed as

Hypoxic ischemic encephalopathyNewbornPerinatal asphyxia

Identifiers

PMID40225795
PMCPMC11981963

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.