Evidence map›Paper›PMID 40225762›Full record

ReviewFrontiers in veterinary science2025

Canine circovirus: emergence, adaptation, and challenges for animal and public health.

Diego Ferreira da Silva, Milene Ciola, Verônica de Oliveira Lopes, Débora Rhayanne Medeiros Matias, Tarley Santos Oliveira, Alessandra Marnie Martins Gomes de Castro

Abstract readReview
In one paragraph

Review in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Diego Ferreira da SilvaSchool of Nursing, University of São Paulo (EEUSP), Graduate Program in Nursing in Adult Health (PROESA), São Paulo, Brazil.
Milene CiolaDepartment of Undergraduate Studies in Veterinary Medicine, Anclivepa College, São Paulo, Brazil.
Verônica de Oliveira LopesDepartment of Undergraduate Studies in Veterinary Medicine, Anclivepa College, São Paulo, Brazil.
Débora Rhayanne Medeiros MatiasPaulista University (UNIP), Graduate Program in Environmental and Experimental Pathology, São Paulo, Brazil.
Tarley Santos OliveiraPaulista University (UNIP), Graduate Program in Environmental and Experimental Pathology, São Paulo, Brazil.
Alessandra Marnie Martins Gomes de CastroPaulista University (UNIP), Graduate Program in Environmental and Experimental Pathology, São Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Canine circovirus (CanineCV) is an emerging pathogen with a significant impact on animal health and potential zoonotic risks. This study addresses its characterization, epidemiology, pathogenesis, and diagnostics, emphasizing its relevance within the One Health approach. Background: The increasing detection of CanineCV across various species and regions highlights its genetic adaptability and cross-species transmission potential. Furthermore, growing interactions among domestic animals, wildlife, and humans amplify the need to understand its public and animal health implications. Objective: To analyze the biology, epidemiology, and diagnostic challenges of CanineCV, focusing on its genetic evolution, interactions with co-infections, and implications for control strategies. Methods: A systematic literature review was conducted, synthesizing data from epidemiological, genomic, and clinical studies. Molecular techniques, such as PCR and qPCR, were evaluated for their efficacy in virus detection and quantification. Results: Canine circovirus exhibits high genetic variability and has been detected in diverse species and tissues. Co-infections, including parvovirus and adenovirus, exacerbate clinical signs, primarily gastrointestinal, and respiratory. Advances in diagnostics, such as real-time PCR and Conclusion: Canine circovirus poses a growing challenge to animal health and a potential threat to public health due to its genetic plasticity and adaptability to multiple hosts. Continuous research is essential to understand its pathogenesis, develop effective control measures, and mitigate risks in diverse ecosystems.

Indexed as

CanineCVCircoviridaeemergingpig diseasePorcine circoviruspublic health

Identifiers

PMID40225762
PMCPMC11987514

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.