Evidence map›Paper›PMID 40225563›Full record

ReviewTheranostics2025

Targeted radioligand therapy: physics and biology, internal dosimetry and other practical aspects during

Habibollah Dadgar, Ali Pashazadeh, Nasim Norouzbeigi, Majid Assadi, Batool Al-Balooshi, Richard P Baum, Akram Al-Ibraheem, Mohamad Haidar, Mohsen Beheshti, Parham Geramifar and 22 more

Abstract readReview
In one paragraph

Review in Theranostics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Progress in the application ofAnnals of nuclear medicine · 2026
    Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Swin UNETR-based prediction of [BMC medical imaging · 2026
    Article
  9. Review
  10. Review
  11. Article
  12. Combination therapy strategies in engineeredCell communication and signaling : CCS · 2026
    Review
  13. Feasibility study ofEJNMMI physics · 2025
    Article
  14. Review
  15. Comparative Analysis ofAdvances in radiation oncology · 2025
    Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors.

Habibollah DadgarCancer Research Center, RAZAVI Hospital, Imam Reza International University, Mashhad, Iran.
Ali PashazadehDepartment of Nuclear Medicine, Mainz University Hospital, Mainz, Germany.
Nasim NorouzbeigiCancer Research Center, RAZAVI Hospital, Imam Reza International University, Mashhad, Iran.
Majid AssadiThe Persian Gulf Nuclear Medicine Research Center, Department of Molecular Imaging and Radionuclide Therapy (MIRT), Bushehr Medical University Hospital, Bushehr University of Medical Sciences, Bushehr, Iran.
Batool Al-BalooshiDubai Nuclear medicine & Molecular imaging Center- Dubai Academic Health corporation- DAHC, United Arab Emirates.
Richard P BaumCURANOSTICUM Wiesbaden-Frankfurt, Center for Advanced Radiomolecular Precision Oncology, Wiesbaden, Germany.
Akram Al-IbraheemDepartment of Nuclear Medicine, King Hussein Cancer Center, Amman, Jordan.
Mohamad HaidarDepartment of Clinical Radiology, American University of Beirut, Beirut, Lebanon.
Mohsen BeheshtiDivision of Molecular Imaging and Theranostics, Department of Nuclear Medicine & Endocrinology, University Hospital, Paracelsus Medical University Salzburg, A-5020 Salzburg, Austria.
Parham GeramifarResearch Center for Nuclear Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Reza ValiNuclear Medicine department, University of Toronto, Hospital for Sick Children, Toronto, Ontario, Canada.
Seyed MohammadiHospital & Health Care Professional, Pittsburgh Medical Center, Nuclear Medicine department, Pittsburg, USA.
Swagat DashDepartment of Nuclear Medicine and Molecular Theranostics, Sarvodaya Hospital, Sector 8, Faridabad, Haryana, India.
Vindhya MalasaniDepartment of Nuclear Medicine and Molecular Theranostics, Sarvodaya Hospital, Sector 8, Faridabad, Haryana, India.
Andrea CiminiNuclear Medicine Unit, St. Salvatore Hospital, 67100 L'Aquila, Italy.
Maria RicciNuclear Medicine Unit, Cardarelli Hospital, 86100 Campobasso, Italy.
Abdulredha A EsmailNuclear Medicine Department, Kuwait Cancer Control Center, Kuwait City, Kuwait.
Sarah MuradNuclear Medicine Department, Kuwait Cancer Control Center, Kuwait City, Kuwait.
Fahad MarafiJaber Alahmad Center of Nuclear Medicine and Molecular Imaging, Kuwait City, Kuwait.
Giorgio TregliaDivision of Nuclear Medicine, Imaging Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland.
Aysar Najeh KhalafNuclear Medicine Department, Warith International Cancer Institute, Karbala, Iraq.
Farah M AnwarNuclear Medicine Department, Warith International Cancer Institute, Karbala, Iraq.
Sharjeel UsmaniDepartment of Nuclear Medicine Sultan Qaboos Comprehensive Cancer Care and Research Center (SQCCCRC), Seeb, Oman.
Yehia OmarPET-CT department at Misr Radiology Center, Heliopolis, Egypt.
Haider MuhsinNuclear Medicine department, Amir Al-Momineen Specialty Hospital, Al-Najaf Governorate, Iraq.
Igore E TyurinMOH Russia, Russian Medical Academy of Continuous Professional Education of the Ministry of Healthcare of the Russian Federation, Russia.
Andrew ZakharyMOH Russia, Russian Medical Academy of Continuous Professional Education of the Ministry of Healthcare of the Russian Federation, Russia.
Sahar Al-SebaieMinistry of National Gaurds Health Services, Jeddah, Saudi Arabia.
Danny Mena CortesOncologia San Jose, UroTeragLATAM, Mexico.
Maryam AlHashimRadiology Department, College of Medicine, Imam Abdulrahman Bin Faisal University, King Faisal Ibn Abd Aziz Rd, Dammam 34212, Saudi Arabia.
Hossein ArabiDivision of Nuclear Medicine and Molecular Imaging, Diagnostic Department, Geneva University Hospital, Geneva, Switzerland.
Habib ZaidiDivision of Nuclear Medicine and Molecular Imaging, Diagnostic Department, Geneva University Hospital, Geneva, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radioligand therapy (RLT) has garnered significant attention due to the recent emergence of innovative and effective theranostic agents, which showed promising therapeutic and prognostic results in various cancers. Moreover, understanding the interaction between different types of radiation and biological tissues is essential for optimizing therapeutic interventions These concepts directly apply to clinical RLTs and play a crucial role in determining the efficacy and toxicity profile of different radiopharmaceutical agents. Personalized dosimetry is a powerful tool that aids in estimating patient-specific absorbed doses in both tumors and normal organs. Dosimetry in RLT is an area of active investigation, as our current understanding of the relationship between absorbed dose and tissue damage is primarily derived from external-beam radiation therapy. Further research is necessary to comprehensively comprehend this relationship in the context of RLTs. In the present review, we present a thorough examination of the involvement of

Indexed as

ActiniumLutetiumNeuroendocrine TumorsProstatic NeoplasmsRadioisotopesRadiopharmaceuticalsAnimalsDNA DamageHumansMaleRadiometryActiniumActinium-225LutetiumLutetium-177RadioisotopesRadiopharmaceuticals177Lu225Ac.DNA damagedosimetryRadiopharmaceutical therapiestheranostics

Identifiers

PMID40225563
PMCPMC11984387

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.