Evidence map›Paper›PMID 40225553›Full record

ArticleCureus2025

A Case Report of Pulmonary Tumor Thrombotic Microangiopathy Caused by Lung Adenocarcinoma: The Importance of Clinical Diagnosis and Monitoring Disease Progression.

Yuta Sakano, Yoko Hamakawa, Ryo Yamanaka, Atsushi Funauchi, Satoshi Marumo, Motonari Fukui

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yuta SakanoRespiratory Disease Center, Medical Research Institute Kitano Hospital, Osaka, JPN.
Yoko HamakawaRespiratory Disease Center, Medical Research Institute Kitano Hospital, Osaka, JPN.
Ryo YamanakaRespiratory Disease Center, Medical Research Institute Kitano Hospital, Osaka, JPN.
Atsushi FunauchiRespiratory Disease Center, Medical Research Institute Kitano Hospital, Osaka, JPN.
Satoshi MarumoRespiratory Disease Center, Medical Research Institute Kitano Hospital, Osaka, JPN.
Motonari FukuiRespiratory Disease Center, Medical Research Institute Kitano Hospital, Osaka, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary tumor thrombotic microangiopathy (PTTM) is a rare and fatal lung complication associated with cancer. Diagnosing PTTM is challenging due to its rapid progression and nonspecific clinical or imaging findings, which often result in postmortem identification. Treatment options are limited, and long-term management remains poorly understood. This report describes a 50-year-old patient with lung adenocarcinoma who was clinically diagnosed with PTTM and showed improvement with early chemotherapy initiation. Disease activity was controlled through multiple chemotherapy regimens, and recurrence was monitored using blood coagulation status and echocardiography. This case highlights the importance of early clinical diagnosis and ongoing monitoring of disease progression in PTTM.

Indexed as

chemotherapylung cancerpulmonary hypertensionpulmonary tumor thrombotic microangiopathyrespiratory failure

Identifiers

PMID40225553
PMCPMC11993430

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.