Evidence map›Paper›PMID 40225542›Full record

ArticleCureus2025

Recognizing Recurrence: History Over Symptoms in Metastatic Melanoma.

John Solomon, Niyousha Naderi, Qui Cheun Ng, Eric Jacobson

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

John SolomonRadiology, KPC Health, Hemet, USA.
Niyousha NaderiDiagnostic Radiology, KPC Health, Hemet, USA.
Qui Cheun NgRadiology, KPC Health, Hemet, USA.
Eric JacobsonRadiology, KPC Health, Hemet, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Imaging findings of diseases are not always very typical. A comprehensive history helps the radiologist make a differential diagnosis list based on likelihood and provides the most helpful report. In this paper, we presented the case of a 41-year-old male with a history of stage IV melanoma with prior brain metastasis and resection who came to the emergency department reporting intermittent headaches, dizziness, vomiting, and a loss of appetite. Diagnostic imaging revealed a right frontal lobe mass concerning recurrent melanoma metastasis. Neurosurgery was consulted, and it was decided to resect the mass. Immunohistochemical staining of the tumor cells confirmed that the lesion was of melanocytic origin. Postoperatively, the patient showed significant improvement in symptoms, with no immediate complications, and continued adjuvant therapies based on the surgical and pathological findings. This case stresses the importance of remaining vigilant for new or worsening symptoms in patients with a history of melanoma, given the aggressive nature of this cancer and the high recurrence rate.

Indexed as

brain metastasismelanoma recurrencemetastatic melanomasurgical resectiont1 hyperintensevasogenic edema

Identifiers

PMID40225542
PMCPMC11993315

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.