ArticleCureus2025
Utilization of Neuroimaging Techniques in the Differential Diagnosis of Very Late-Onset Schizophrenia and Neurodegenerative Disorders.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The emergence of psychiatric symptoms in late life presents a diagnostic challenge due to their overlap with neurodegenerative disorders. This case details a 66-year-old male with acute psychosis, initially raising concerns for an underlying neurodegenerative-related process. Comprehensive evaluation, including neuroimaging and laboratory studies, excluded neurodegeneration, leading to a diagnosis of very late-onset schizophrenia. The patient demonstrated clinical improvement with an atypical antipsychotic, while an acetylcholinesterase inhibitor was discontinued due to the absence of neurodegenerative pathology. This case highlights the critical role of thorough diagnostic assessment in differentiating primary psychiatric disorders from neurodegenerative conditions in older adults.
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