ReviewCureus2025
Chlorhexidine Gluconate in Pediatric Endodontic Treatment: A Scoping Review.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chlorhexidine digluconate (CHX) is widely recognized for its antimicrobial properties and potential use as an irrigant in endodontic treatment. However, its specific role in the treatment of primary teeth remains uncertain. This review aimed to evaluate the effectiveness of CHX in cleaning the root canal system in pediatric endodontic treatment. A total of 46 studies were initially identified from three databases: PubMed (5), ScienceDirect (2), and Cochrane (0). Following selection based on PRISMA-ScR 2018 guidelines, seven studies met all inclusion criteria and were included in the qualitative analysis. The findings indicate that CHX 2% demonstrates good antibacterial efficacy but lacks the ability to dissolve inorganic tissue. Additionally, its safety and effectiveness in dissolving organic tissue in primary teeth have yet to be thoroughly investigated. The minimum irrigation volume when using CHX is 2 ml per root canal, which ensures optimal effectiveness in bacterial elimination and improves treatment outcomes. While CHX shows promise as an endodontic irrigation solution for primary teeth, further research is necessary to fully understand its potential benefits and limitations.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.