ArticleCureus2025
Comparative Evaluation of the Antimicrobial Efficacy of Endodontic Sealers Against Staphylococcus aureus and Streptococcus mutans: An In Vitro Study.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Article
- Article
- Recent progress in antimicrobial strategies of controlled-release nanomaterials for secondary caries.Frontiers in cellular and infection microbiology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionEndodontic therapy aims to eliminate microbial infections from the root canal system and prevent reinfection, thus ensuring periapical tissue healing. Persistent bacterial contamination, particularly from MATERIALS AND
methodsThis in vitro study was conducted at the Department of Conservative Dentistry and Endodontics between May 2024 and October 2024. The antimicrobial properties of three endodontic sealers - AH Plus, ZOE sealer, and Tubli Seal - were tested against
resultsAt 24 hours, AH Plus exhibited the highest antimicrobial activity against both bacterial species (p < 0.05), followed by the Tubli Seal and ZOE. By seven days, the ZOE sealer demonstrated the most potent antibacterial effect, surpassing AH Plus and Tubli Seal (p < 0.05). Both AH Plus and Tubli Seal exhibited a decline in the antibacterial activity over time. All the sealers were more effective against
conclusionEndodontic sealers exhibit time-dependent antibacterial properties. AH Plus is the most effective sealer in the early stages of treatment, providing strong initial bacterial suppression, whereas ZOE sealer demonstrated sustained antimicrobial activity over time. The Tubli Seal showed moderate efficacy. These findings emphasize the importance of sealer selection based on clinical scenarios.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.