Evidence map›Paper›PMID 40225414›Full record

ArticleOxidative medicine and cellular longevity2025

Efficacy of Plasmalogens on Monosodium Glutamate-Induced Neurotoxicity in Male Rats Through NF-

Heba M Abdou, Fatma A Hamaad, Ghada M Abd Elmageed, Hideki Katano, Mamdooh H Ghoneum

Abstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Heba M AbdouDepartment of Zoology, Alexandria University, Alexandria, Egypt.
Fatma A HamaadDepartment of Biochemistry, Alexandria University, Alexandria, Egypt.
Ghada M Abd ElmageedDepartment of Zoology, Alexandria University, Alexandria, Egypt.
Hideki KatanoInstitute of Gerontology, Adachi-ku, Tokyo, Japan.
Mamdooh H GhoneumDepartment of Surgery, Charles R. Drew University of Medicine and Science, Los Angeles, California, USA.ORCID https://orcid.org/0000-0002-1087-7127

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Monosodium glutamate (MSG) is the most commonly used food additive and has well-known neurotoxic effects. The current study was carried out to assess the underlying mechanisms of the neurotoxicity of MSG on the hippocampus in male rats and examine the protective effect of plasmalogens (Pls) on nuclear factor-B (NF-

Indexed as

MAP Kinase Signaling SystemNF-kappa Bp38 Mitogen-Activated Protein KinasesPlasmalogensSodium GlutamateAnimalsHippocampusMaleOxidative StressRatsRats, WistarSignal TransductionNF-kappa Bp38 Mitogen-Activated Protein KinasesPlasmalogensSodium Glutamatemonosodium glutamateneurochemical markersneurodegenerationp38 MAPKplasmalogens

Identifiers

PMID40225414
PMCPMC11991862

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.