ArticleRespiratory medicine case reports2025
A young female with multiple cavitary lung lesions.
Article in Respiratory medicine case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A 21-year-old female with a history of HPV and recurrent laryngeal papillomatosis has required frequent removal of laryngeal papilloma through direct laryngoscopy and has been treated with interferon alpha since she was 7 months old. She now presented with worsening dyspnea, hemoptysis, night sweats and significant weight loss. Infectious work up was negative. CT thorax showed significantly increasing right lower lobe mass with thick septation, debris and fluid concerning for malignant transformation. CT-guided biopsy of the mass showed features concerning for necrotic squamous cell carcinoma (SCC). Multidisciplinary tumor board classified this as malignant transformation due to bilateral lungs involvement and aggressive nature of the disease and recommended treatment with combination of chemotherapy and immunotherapy. Unfortunately, she continued to have declining performance status with multiple hospitalizations for hypoxic respiratory failure. Repeat CT scan of the chest showed progression of the lung lesions with extensive mediastinal involvement. She was unable to tolerate any additional therapy and decided with her family to pursue inpatient hospice. Malignant transformation into squamous cell carcinoma in recurrent respiratory papillomatosis is rare and is associated with worse outcomes.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.