ArticleMaterials today. Bio2025
Micro-fragmented collagen hydrogel wound dressing: Enhanced porosity facilitates elevated stem cell survival and paracrine effects for accelerated wound maturation.
Article in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Supercritical COMaterials today. Bio · 2026Article
- Collagen-Enriched Immunomodulatory Hydrogel for Tendon Regeneration.Gels (Basel, Switzerland) · 2026Article
- Microneedle Strategies for Diabetic Wound Management: A Comprehensive Review of Materials, Mechanisms, and Therapeutic Outcomes.Materials today. Advances · 2026Article
- Stem Cell and Exosome Therapy in Wound Healing: Traps, Paradoxes, and Tricks Transforming Paradigms.Biomedicines · 2025Article
- A dual-component particulate dressing for simultaneous microenvironment modulation and tissue regeneration in infected diabetic wounds.Materials today. Bio · 2025Article
- Towards Intelligent Wound Care: Hydrogel-Based Wearable Monitoring and Therapeutic Platforms.Polymers · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Human Adipose-derived stem cells (hADSCs), known for their mesenchymal stem cell properties, including multilineage differentiation and self-renewal, hold significant promise for chronic wound regeneration. Typically, hADSCs are utilized in cellular aggregates or hydrogels to enhance therapeutic efficacy. However, limitations such as reduced cell viability, inadequate mass transfer rates, and diminished paracrine effects hinder their clinical applications. This study explores an innovative approach by encapsulating hADSCs within a collagen/hyaluronic acid micro-fragmented collagen hydrogel wound dressing (MCWD). The resulting micro-fragmented collagen hydrogel-hADSC composite created through the integration of micro-sized hydrogel units and cells demonstrated markedly improved cell viability and activity, as well as superior therapeutic outcomes compared to conventional cell aggregates (CA) and collagen hydrogel wound dressings (CWD
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.