Evidence map›Paper›PMID 40225034›Full record

ReviewJournal of circadian rhythms2025

Mini review: Bidirectional Regulation of Circadian Rhythm by Suprachiasmatic Nucleus and Nuclear Receptors in Female Mammals.

Dharani Abirama Sundari Shanmugam, Ashwini Devi Balaraman, Abhijit Kar, Abishek Franco, B Arjun Chandra Balaji, S Meenakumari, P K Praveenkumar, R Gayathri, Vinoth Kumar Ganesan, Merugumolu Vijay Kumar and 2 more

Abstract readReview
In one paragraph

Review in Journal of circadian rhythms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Dharani Abirama Sundari ShanmugamDepartment of Endocrinology, Dr. ALM. PG. Institute of Basic Medical Sciences, University of Madras, Taramani, Chennai - 600113, Tamil Nadu, India.ORCID https://orcid.org/0000-0001-6936-0299
Ashwini Devi BalaramanDepartment of Biotechnology, School of Bioengineering, SRM Institute of Science and Technology, Kattankulathur - 603202, Tamil Nadu, India.ORCID https://orcid.org/0000-0002-9023-4235
Abhijit KarDepartment of Biotechnology, School of Bioengineering, SRM Institute of Science and Technology, Kattankulathur - 603202, Tamil Nadu, India.ORCID https://orcid.org/0009-0006-9571-9852
Abishek FrancoDepartment of Biotechnology, School of Bioengineering, SRM Institute of Science and Technology, Kattankulathur - 603202, Tamil Nadu, India.ORCID https://orcid.org/0000-0002-4913-3686
B Arjun Chandra BalajiDepartment of Computer Science, Dalhousie University, Halifax, Nova Scotia, B3H 4R2, Canada.ORCID https://orcid.org/0009-0007-3562-0858
S MeenakumariDepartment of Biotechnology, School of Bioengineering, SRM Institute of Science and Technology, Kattankulathur - 603202, Tamil Nadu, India.ORCID https://orcid.org/0000-0002-3743-1133
P K PraveenkumarDepartment of Biotechnology, Sri Venkateswara College of Engineering, Sriperumbudur Tk - 602117, Tamil Nadu, India.ORCID https://orcid.org/0000-0002-8915-3542
R GayathriDepartment of Biotechnology, St Joseph's College of Engineering, Old Mahabalipuram Road, Kamaraj Nagar, Semmancheri, Chennai - 600119, Tamil Nadu, India.ORCID https://orcid.org/0000-0002-0093-9777
Vinoth Kumar GanesanDepartment of Health Research (DHR-ICMR), Multi-Disciplinary Research Unit (MRU), Rangaraya Medical College, Kakinada - 533003, Andhra Pradesh, India.ORCID https://orcid.org/0000-0003-3673-6717
Merugumolu Vijay KumarDepartment of Pharmacology, Dayananda Sagar University, Bengaluru - 560078, Karnataka, India.ORCID https://orcid.org/0000-0002-8366-6312
K SenthilkumarMr. & Mrs. Ko Chi-Ming Centre for Parkinson's Disease Research, School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong Special Administrative Region of China.ORCID https://orcid.org/0000-0001-8799-7357
B ShanthiDepartment of Biotechnology, JAASB Institute and Research Academia, Valasaravakkam, Chennai - 600087, Tamil Nadu, India.ORCID https://orcid.org/0009-0003-5697-252X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The anterior region of the hypothalamus accommodates a bilateral structure called the suprachiasmatic nucleus (SCN), which controls, modulates, and perpetuates the homeostasis of circadian rhythm and sleep hormone release. These SCN have a predominance over multitudinous peripheral tissues like the uterus, liver, intestine, pancreas, endocrine system, immune system, reproductive system, and cardiovascular system. This peripheral clock acts as a pacemaker for circadian rhythm timing, which regulates crucial metabolic pathways and organizes numerous activities in the female reproductive network of mammals. The circadian

Indexed as

Circadian rhythmCLOCK genesnuclear receptorssuprachiasmatic nucleus (SCN)

Identifiers

PMID40225034
PMCPMC11987856

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.