Evidence map›Paper›PMID 40224974›Full record

ArticleTranslational cancer research2025

Biological and clinical significance of circulating mucosal-associated invariant T cells in lung cancer.

Jingjing Liu, Haoyu Wang, Xiaotao Wang, Jacek Jassem, Jiming Si, Yuanhua Liu, Jianjun Jin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Translational cancer research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jingjing Liu *Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Haoyu Wang *Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Xiaotao WangPulmonary and Critical Care Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Jacek JassemDepartment of Oncology and Radiotherapy, Medical University of Gdańsk, Gdańsk, Poland.
Jiming SiPulmonary and Critical Care Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yuanhua LiuPulmonary and Critical Care Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Jianjun JinPulmonary and Critical Care Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Lung cancer is among the most common malignant tumors worldwide. Circulating mucosal-associated invariant T (cMAIT) cells play an important role in cancer. This study investigated the biological and clinical significance of cMAIT cells in lung cancer. Methods: Fasting peripheral blood mononuclear cells (PBMCs) were extracted from 30 newly diagnosed lung cancer patients and 30 healthy controls. The percentages of cMAIT among the CD3 Results: The percentages and absolute values of the cMAIT in lung cancer patients were lower than in healthy subjects (P<0.001, P<0.01, respectively). The CD8 Conclusions: Lower percentage and absolute values of cMAIT in lung cancer patients may be due to their migration into tissues. The number of cMAIT in lung cancer patients may potentially be considered as a prognostic indicator.

Indexed as

lung cancerMucosal-associated invariant T cells (MAIT cells)prognosis

Identifiers

PMID40224974
PMCPMC11985213

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.