ArticleTranslational cancer research2025
Induction of ferroptosis in oxaliplatin-resistant colorectal cancer cells by extract from
Article in Translational cancer research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Colorectal cancer (CRC) is the third most common cancer worldwide, and there is growing number of reports on the emergence of chemoresistance among patients with CRC. Oxaliplatin, a common chemotherapeutic agent used to treat CRC, has been linked to the emergence of drug-resistant tumor cells. While traditional Chinese medicines have gained attention for their multi-target anticancer properties, Methods: Oxaliplatin-resistant HT29 CRC cells were generated by increasing the concentration of oxaliplatin in the culture media. Cell viability was measured via MTT (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium-bromide) assay, while proliferation was assessed via wound healing assays. Gene expression was determined with quantitative polymerase chain reaction and Western blotting. Extract from Results: Treatment with Conclusions:
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