Evidence map›Paper›PMID 40224904›Full record

ArticleFrontiers in health services2025

Co-creating strategies to promote uptake of HIV self-testing among young adults in Mecklenburg county, North Carolina: a protocol for a pilot implementation study.

Ucheoma Nwaozuru, Lindsay Miller, Laura H Gunn, Sebastian Marin-Cespedes, Margaret Hanff, Patrick Robinson, Michael Dulin, Meghana Muralidhar, Prashant Jha, Goodness C Mirikwe and 6 more

Abstract read
In one paragraph

Article in Frontiers in health services, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Ucheoma NwaozuruDepartment of Implementation Science, Division of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, NC, United States.
Lindsay MillerDepartment of Epidemiology and Community Health, College of Health and Human Services, University of North Carolina at Charlotte, Charlotte, NC, United States.
Laura H GunnDepartment of Epidemiology and Community Health, College of Health and Human Services, University of North Carolina at Charlotte, Charlotte, NC, United States.
Sebastian Marin-CespedesDepartment of Epidemiology and Community Health, College of Health and Human Services, University of North Carolina at Charlotte, Charlotte, NC, United States.
Margaret HanffDepartment of Epidemiology and Community Health, College of Health and Human Services, University of North Carolina at Charlotte, Charlotte, NC, United States.
Patrick RobinsonDepartment of Health Policy and Management and the Academy for Population Health Innovation, College of Health and Human Services, University of North Carolina at Charlotte, Charlotte, NC, United States.
Michael DulinDepartment of Health Policy and Management and the Academy for Population Health Innovation, College of Health and Human Services, University of North Carolina at Charlotte, Charlotte, NC, United States.
Meghana MuralidharCollege of Health and Human Services, University of North Carolina at Charlotte, Charlotte, NC, United States.
Prashant JhaMusculoskeletal Institute, Atrium Health Carolinas Medical Center, Charlotte, NC, United States.
Goodness C MirikweDepartments of Biology and Chemistry, Wake Forest University, Winston-Salem, NC, United States.
Donaldson F ConserveDepartment of Prevention and Community Health, Milken Institute School of Public Health, George Washington University, Washington, DC, United States.
Chelsea GuldenRAIN Inc., Charlotte, NC, United States.
Bernard A DavisRAO Community Health, Charlotte, NC, United States.
Kristie FoleyDepartment of Implementation Science, Division of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, NC, United States.
Joseph TuckerDepartment of Medicine, Division of Infectious Diseases, University of North Carolina at Chapel-Hill School of Medicine, Chapel-Hill, NC, United States.
Meagan ZarwellDepartment of Epidemiology and Community Health, College of Health and Human Services, University of North Carolina at Charlotte, Charlotte, NC, United States.

Funding

Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
NIAID NIH HHS P30 AI050410
6 · The paper itself

Abstract

Background: HIV testing is the gateway to entering HIV care and prevention services. However, HIV testing rates remain low among young adults (18-29 years old) in Mecklenburg County, North Carolina (NC), an ending the HIV epidemic (EHE) priority jurisdiction. We aim to utilize community-engaged and participatory approaches to co-create implementation strategies to promote the reach and uptake of HIV self-testing (HIVST) among young adults in the region. This study protocol outlines the phases of the project and the proposed outcomes. Methods: The Community-engaged Approaches to Expand HIV Self-Testing among Young Adults in Mecklenburg County, North Carolina (CATEST) project will be conducted in three phases, guided by the Consolidated Framework for Implementation Research (CFIR), Community-based Participatory Research (CBPR), and Reach, Effectiveness, Adoption, Implementation, and Maintenance (RE-AIM) frameworks. The formative phase of the study, guided by CFIR, will focus on understanding the barriers, facilitators, and opportunities for implementing HIVST among young adults in Mecklenburg County, North Carolina. The second phase, guided by CBPR, will utilize participatory approaches such as crowdsourcing open calls and charrettes to co-create implementation strategies for HIVST. Then, the final pilot implementation phase, guided by CFIR and RE-AIM, will use mixed methods to evaluate the success of the co-created HIVST implementation strategies using a pre-post design. Participants in the study will complete a baseline survey and a follow-up survey immediately following intervention completion. In addition, a purposive sample of participants and representatives at the participating community organization will complete qualitative exit interviews within 1 month of intervention completion. Discussion: This study protocol outlines the co-creation of implementation strategies, tests their feasibility, and explores preliminary effectiveness in promoting HIVST uptake among young adults in Mecklenburg County, NC. The study will yield insights on the feasibility of leveraging the capabilities of community and youth innovation to promote young adults-centered implementation strategies to advance the reach and adoption of HIVST among young adults. Registration: Registered on Open Science Forum-DOI 10.17605/OSF.IO/2BZWV.

Indexed as

community-based participatory approachescrowdsourcingHIV self-testingNorth Carolinayoung adults

Identifiers

PMID40224904
PMCPMC11985853

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.