Evidence map›Paper›PMID 40224657›Full record

ArticleBio-protocol2025

Screening for

Andy Caballero Méndez, Roberto A Reynoso de La Rosa, Miguel E Abreu Bencosme, Mayeline N Sosa Ortiz, Eliezel Pichardo Beltré, Darah M de La Cruz García, Nelson J Piñero Santana, Joana C Bacalhau de León

Abstract read
In one paragraph

Article in Bio-protocol, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Andy Caballero MéndezMolecular Biology Department, Referencia Laboratorio Clínico, Zona Industrial de Herrera, Santo Domingo Oeste, Santo Domingo, Dominican Republic.
Roberto A Reynoso de La RosaMolecular Biology Department, Referencia Laboratorio Clínico, Zona Industrial de Herrera, Santo Domingo Oeste, Santo Domingo, Dominican Republic.
Miguel E Abreu BencosmeMolecular Biology Department, Referencia Laboratorio Clínico, Zona Industrial de Herrera, Santo Domingo Oeste, Santo Domingo, Dominican Republic.
Mayeline N Sosa OrtizMolecular Biology Department, Referencia Laboratorio Clínico, Zona Industrial de Herrera, Santo Domingo Oeste, Santo Domingo, Dominican Republic.
Eliezel Pichardo BeltréMolecular Biology Department, Referencia Laboratorio Clínico, Zona Industrial de Herrera, Santo Domingo Oeste, Santo Domingo, Dominican Republic.
Darah M de La Cruz GarcíaMolecular Biology Department, Referencia Laboratorio Clínico, Zona Industrial de Herrera, Santo Domingo Oeste, Santo Domingo, Dominican Republic.
Nelson J Piñero SantanaMolecular Biology Department, Referencia Laboratorio Clínico, Zona Industrial de Herrera, Santo Domingo Oeste, Santo Domingo, Dominican Republic.
Joana C Bacalhau de LeónMicrobiology Department, Referencia Laboratorio Clínico, Zona Industrial de Herrera, Santo Domingo Oeste, Santo Domingo, Dominican Republic.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Laboratory-developed tests (LDTs) are optimal molecular diagnostic modalities in circumstances such as public health emergencies, rare disease diagnosis, limited budget, or where existing commercial alternatives are unavailable, limited in supply, or withdrawn, either temporarily or permanently. These tests reduce access barriers and enhance equitable clinical practice and healthcare delivery. Despite recommendations for the development of nucleic acid amplification tests, procedural details are often insufficient, inconsistent, and arbitrary. This protocol elucidates the methodology used in the development of a fully automated real-time polymerase chain reaction (qPCR)-based test, using the Panther Fusion

Indexed as

Group B Streptococcus (GBS) screeningLaboratory-developed testMolecular diagnosticsOligo designPanther Fusion® Open AccessTMReal-time PCR (qPCR)

Identifiers

PMID40224657
PMCPMC11986707

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.