ArticleInternational journal of cardiology. Heart & vasculature2025
The impact of empirical superior vena cava isolation in addition to pulmonary vein isolation on outcomes in atrial fibrillation - Systematic review, meta-analysis, and meta-regression.
Article in International journal of cardiology. Heart & vasculature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Circumferential pulmonary vein isolation with adjunctive linear ablation vs. circumferential pulmonary vein isolation alone for long-standing persistent atrial fibrillation: a randomized pilot study.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025Trial
- Recent highlights from theInternational journal of cardiology. Heart & vasculature · 2026Article
- Superior vena cava isolation with 3D mapping using a novel balloon-in-basket pulsed field ablation catheter.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026Article
- Recent highlights from theInternational journal of cardiology. Heart & vasculature · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Atrial tachyarrhythmia (ATa) recurrence remains high after pulmonary vein isolation (PVI), with the superior vena cava (SVC) being a common source of non-pulmonary vein foci. Objective: This Methods: A systematic review was conducted on studies comparing eSVCi to no eSVCi (PVI-only or adjunctive SVC isolation). The primary outcome was ATa recurrence, defined as AF/atrial flutter/atrial tachycardia lasting over 30 s after a blanking period. Secondary outcomes included procedural duration, fluoroscopic duration, and complications. Results: Thirteen studies involving 2,176 patients were analyzed, with a mean follow-up of 18 ± 9.6 months. ATa recurrence was significantly lower with eSVCi (OR 0.54 [95 % CI: 0.41, 0.72], p < 0.001; I Conclusion: eSVCi potentially reduce ATa recurrence compared to no eSVCi, without increasing complications or prolonging procedural times.
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