Evidence map›Paper›PMID 40224610›Full record

ArticleDepression and anxiety2023

Depressive Symptoms are Associated with More Negative Global Metacognitive Biases in Combat Veterans, and Biases Covary with Symptom Changes over Time.

Sam Agnoli, Agnieszka Zuberer, Melanni Nanni-Zepeda, Regina E McGlinchey, William P Milberg, Michael Esterman, Joseph DeGutis

Abstract read
In one paragraph

Article in Depression and anxiety, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Measure twice, cut once: Moving toward more inclusive, principled criteria for diagnosing developmental prosopagnosia.Cortex; a journal devoted to the study of the nervous system and behavior · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sam AgnoliTranslational Research Center for TBI and Stress Disorders (TRACTS) and Geriatric Research, Education and Clinical Center (GRECC), VA Boston Health Care System, Boston, MA, USA.ORCID 0000-0001-9196-7855
Agnieszka ZubererDepartment for Psychiatry and Psychotherapy, University Hospital Tübingen, Tübingen, Germany.ORCID 0000-0001-6547-298X
Melanni Nanni-ZepedaDepartment for Psychiatry and Psychotherapy, University Hospital Tübingen, Tübingen, Germany.ORCID 0000-0003-3349-6164
Regina E McGlincheyTranslational Research Center for TBI and Stress Disorders (TRACTS) and Geriatric Research, Education and Clinical Center (GRECC), VA Boston Health Care System, Boston, MA, USA.ORCID 0000-0003-4809-1194
William P MilbergTranslational Research Center for TBI and Stress Disorders (TRACTS) and Geriatric Research, Education and Clinical Center (GRECC), VA Boston Health Care System, Boston, MA, USA.ORCID 0000-0002-6078-7066
Michael EstermanBoston Attention and Learning Lab, VA Boston Health Care System, Boston, MA, USA.ORCID 0000-0002-9000-3920
Joseph DeGutisTranslational Research Center for TBI and Stress Disorders (TRACTS) and Geriatric Research, Education and Clinical Center (GRECC), VA Boston Health Care System, Boston, MA, USA.ORCID 0000-0002-7148-9654

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metacognitive awareness, insight into one's abilities, is thought to be disrupted in depression and posttraumatic stress disorder (PTSD), with more negative metacognitive biases and reduced awareness, respectively. However, studies have rarely examined global aspects of metacognitive awareness in depression and PTSD, instead using task-specific measures. In 467 trauma-exposed post-9/11 veterans, we administered assessments of PTSD and depression, self-report and objective measures of cognitive functioning (neuropsychological battery of memory, attention, and executive function measures), and self-report and objective measures of general health (index of five cardiometabolic factors). We used self-report/objective correlations to measure metacognitive sensitivity and 'self-report minus objective' scores to measure bias. We also examined associations between changes in metacognitive awareness and changes in PTSD and depression over time. Metacognitive sensitivity was comparable between individuals with and without PTSD and depression. However, metacognitive bias was significantly more negative in those with greater depressive symptoms (i.e., underconfidence) across cognition and health, independent of PTSD symptoms. Notably, metacognitive bias changes covaried with depressive and PTSD symptom changes two years later. This shows that, in trauma-exposed veterans, negative metacognitive biases are specifically related to depressive symptoms and these biases may be relatively domain general. Further, our longitudinal results suggest that, rather than being a stable trait, metacognitive biases change with PTSD/depressive symptoms over time.

Indexed as

DepressionMetacognitionStress Disorders, Post-TraumaticVeteransAdultFemaleHumansMaleMiddle Aged

Identifiers

PMID40224610
PMCPMC11921826

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.