Evidence map›Paper›PMID 40224607›Full record

ArticleDepression and anxiety2023

Individual-Level Prediction of Exposure Therapy Outcome Using Structural and Functional MRI Data in Spider Phobia: A Machine-Learning Study.

Alice V Chavanne, Charlotte Meinke, Till Langhammer, Kati Roesmann, Joscha Boehnlein, Bettina Gathmann, Martin J Herrmann, Markus Junghoefer, Luisa Klahn, Hanna Schwarzmeier and 7 more

Abstract read
In one paragraph

Article in Depression and anxiety, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Artificial Intelligence-Empowered Multimodal Learning in Psychiatry: A Scoping Review.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2026
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Alice V ChavanneDepartment of Psychology, Humboldt-Universität zu Berlin, Berlin, Germany.ORCID 0000-0002-5860-2237
Charlotte MeinkeDepartment of Psychology, Humboldt-Universität zu Berlin, Berlin, Germany.
Till LanghammerDepartment of Psychology, Humboldt-Universität zu Berlin, Berlin, Germany.ORCID 0000-0001-6729-956X
Kati RoesmannInstitute of Clinical Psychology and Psychotherapy, University of Siegen, Germany.ORCID 0000-0001-6940-3551
Joscha BoehnleinInstitute for Translational Psychiatry, University of Münster, Germany.ORCID 0000-0002-9870-5599
Bettina GathmannInstitute of Medical Psychology and Systems Neuroscience, University of Münster, Germany.ORCID 0000-0002-5135-4242
Martin J HerrmannDepartment of Psychiatry, Psychosomatics, and Psychotherapy, Center for Mental Health, University Hospital of Würzburg, Germany.ORCID 0000-0001-9970-2122
Markus JunghoeferInstitute for Biomagnetism and Biosignalanalysis, University of Münster, Germany.ORCID 0000-0002-8532-2986
Luisa KlahnDepartment of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, University of Gothenburg, Sweden.ORCID 0000-0002-9189-6687
Hanna SchwarzmeierDepartment of Psychiatry, Psychosomatics, and Psychotherapy, Center for Mental Health, University Hospital of Würzburg, Germany.ORCID 0000-0002-7341-4744
Fabian R SeegerDepartment of Psychiatry, Psychosomatics, and Psychotherapy, Center for Mental Health, University Hospital of Würzburg, Germany.
Niklas SiminskiDepartment of Psychiatry, Psychosomatics, and Psychotherapy, Center for Mental Health, University Hospital of Würzburg, Germany.
Thomas StraubeInstitute for Translational Psychiatry, University of Münster, Germany.
Udo DannlowskiInstitute for Translational Psychiatry, University of Münster, Germany.ORCID 0000-0002-0623-3759
Ulrike LuekenDepartment of Psychology, Humboldt-Universität zu Berlin, Berlin, Germany.ORCID 0000-0003-1564-4012
Elisabeth J LeehrInstitute for Translational Psychiatry, University of Münster, Germany.
Kevin HilbertDepartment of Psychology, Humboldt-Universität zu Berlin, Berlin, Germany.ORCID 0000-0002-7986-4113

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Machine-learning prediction studies have shown potential to inform treatment stratification, but recent efforts to predict psychotherapy outcomes with clinical routine data have only resulted in moderate prediction accuracies. Neuroimaging data showed promise to predict treatment outcome, but previous prediction attempts have been exploratory and reported small clinical sample sizes. Herein, we aimed to examine the incremental predictive value of neuroimaging data in contrast to clinical and demographic data alone (for which results were previously published), using a two-level multimodal ensemble machine-learning strategy. We used pretreatment structural and task-based fMRI data to predict virtual reality exposure therapy outcome in a bicentric sample of

Indexed as

BrainImplosive TherapyMachine LearningMagnetic Resonance ImagingOutcome Assessment, Health CarePhobic DisordersVirtual Reality Exposure TherapyAdultAnimalsFemaleHumansMaleMiddle AgedSpidersTreatment OutcomeYoung Adult

Identifiers

PMID40224607
PMCPMC11921848

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.