Evidence map›Paper›PMID 40224574›Full record

ArticleJournal of the Canadian Association of Gastroenterology2025

A multivariable prediction model to stratify risk of 90-day rehospitalization among adults with ulcerative colitis.

Claudia Dziegielewski, Sarang Gupta, Julia Lombardi, Erin Kelly, Jeffrey D McCurdy, Richmond Sy, Nav Saloojee, Tim Ramsay, Michael Pugliese, Jahanara Begum and 2 more

Abstract read
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In one paragraph

Article in Journal of the Canadian Association of Gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Claudia DziegielewskiDepartment of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.ORCID https://orcid.org/0000-0002-7309-1316
Sarang GuptaDepartment of Medicine, University of Toronto, Toronto, ON M5S 3H2, Canada.ORCID https://orcid.org/0000-0002-4367-2216
Julia LombardiDepartment of Medicine, McMaster University, Hamilton, ON L8N 3Z5, Canada.
Erin KellyDivision of Gastroenterology, Department of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.
Jeffrey D McCurdyDivision of Gastroenterology, Department of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.
Richmond SyDivision of Gastroenterology, Department of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.ORCID https://orcid.org/0000-0002-9085-6085
Nav SaloojeeDivision of Gastroenterology, Department of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.
Tim RamsayOttawa Hospital Research Institute, University of Ottawa, Ottawa, ON K1H 8L6, Canada.
Michael PuglieseOttawa Hospital Research Institute, University of Ottawa, Ottawa, ON K1H 8L6, Canada.
Jahanara BegumOttawa Hospital Research Institute, University of Ottawa, Ottawa, ON K1H 8L6, Canada.
Eric I BenchimolDivision of Gastroenterology, Hepatology and Nutrition, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada.
Sanjay K MurthyDivision of Gastroenterology, Department of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Individuals with ulcerative colitis (UC) are frequently re-hospitalized for persistent or recurrent severe disease flares. Accurate prediction of the risk of early re-hospitalization at the time of discharge could promote targeted outpatient interventions to reduce this risk. Methods: We conducted a retrospective study in adults with UC admitted to The Ottawa Hospital between 2009 and 2016 for an acute UC-related indication. We ascertained candidate demographic, clinical, and health services predictors through medical records and administrative health databases. We derived and bootstrap validated a multivariable logistic regression model of 90-day UC-related re-hospitalization risk. We chose a probability cut point that maximized Youden's index to differentiate high-risk from low-risk individuals and assessed model performance. Results: Among 248 UC-related hospitalizations, there were 27 (10.9%) re-hospitalizations within 90 days of discharge. Our multivariable model identified gastroenterologist consultation within the prior year (adjusted odds ratio [aOR] 0.11, 95% confidence interval [CI], 0.04-0.39), male sex (aOR 3.27, 95% CI, 1.33-8.05), length of stay (OR 0.94, 95% CI, 0.88-1.01), and narcotic prescription at discharge (OR 1.96, 95% CI, 0.73-5.27) as significant predictors of 90-day re-hospitalization. The optimism-corrected Conclusions: A limited set of variables accessible at the point of hospital discharge can reasonably discriminate re-hospitalization risk among individuals with UC. Future studies are required to validate our findings.

Indexed as

inflammatory bowel diseasepredictive modelre-hospitalizationrisk stratificationulcerative colitis

Identifiers

PMID40224574
PMCPMC11991872

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.