Evidence map›Paper›PMID 40224485›Full record

ArticleMediators of inflammation2025

Causal Associations of Inflammatory Cytokines With Osteosarcopenia: Insights From Mendelian Randomization and Single Cell Analysis.

Zugui Wu, Jiyong Yang, Yue Zhu, Jiao Li, Kang Xu, Yuanlong Li, Guoqing Zhong, Yanfei Xu, Ying Guo, Yu Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Mediators of inflammation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zugui WuDepartment of Bone Tumor, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou 510000, Guangdong, China.ORCID https://orcid.org/0000-0002-0564-0643
Jiyong YangDepartment of Orthopaedic, The Fifth Clinical College of Guangzhou University of Chinese Medicine, Guangzhou 510000, Guangdong, China.ORCID https://orcid.org/0000-0002-7681-5316
Yue ZhuDepartment of Orthopaedic, The Third Affiliated Hospital of Yunnan University of Chinese Medicine, Kunming Municipal Hospital of Traditional Chinese Medicine, Kunming 650000, Yunnan, China.ORCID https://orcid.org/0000-0002-4610-8610
Jiao LiDepartment of Orthopaedic, The Third Affiliated Hospital of Yunnan University of Chinese Medicine, Kunming Municipal Hospital of Traditional Chinese Medicine, Kunming 650000, Yunnan, China.ORCID https://orcid.org/0009-0003-0270-4319
Kang XuDepartment of Orthopaedic, The Third Affiliated Hospital of Yunnan University of Chinese Medicine, Kunming Municipal Hospital of Traditional Chinese Medicine, Kunming 650000, Yunnan, China.
Yuanlong LiDepartment of Bone Tumor, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou 510000, Guangdong, China.
Guoqing ZhongDepartment of Bone Tumor, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou 510000, Guangdong, China.
Yanfei XuDepartment of Orthopaedic, The Third Affiliated Hospital of Yunnan University of Chinese Medicine, Kunming Municipal Hospital of Traditional Chinese Medicine, Kunming 650000, Yunnan, China.
Ying GuoDepartment of Orthopaedic, The Third Affiliated Hospital of Yunnan University of Chinese Medicine, Kunming Municipal Hospital of Traditional Chinese Medicine, Kunming 650000, Yunnan, China.ORCID https://orcid.org/0009-0007-2015-9878
Yu ZhangDepartment of Bone Tumor, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou 510000, Guangdong, China.ORCID https://orcid.org/0000-0003-2321-7918

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CytokinesMendelian Randomization AnalysisSarcopeniaSingle-Cell AnalysisGenome-Wide Association StudyHumansInflammationMaleOsteoporosisCytokinescytokinesinflammationmendelian randomizedosteosarcopeniasingle-cell sequencing

Identifiers

PMID40224485
PMCPMC11986192

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.