Evidence map›Paper›PMID 40224443›Full record

ArticleACS omega2025

Enhanced Antitumor and Antibacterial Activities of Ursolic Acid through β-Cyclodextrin Inclusion Complexation.

Júlia B Fajardo, Mariana H Vianna, Thayná G Ferreira, Ari S de O Lemos, Thalita de F Souza, Lara M Campos, Priscila de L Paula, Nubia B Andrade, Lívia R Gamarano, Lucas S Queiroz and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Unraveling the Effects ofInternational journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Júlia B FajardoLaboratory of Bioactive Natural Products, Department of Biochemistry, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, Minas Gerais CEP 36036-900, Brazil.
Mariana H ViannaLaboratory of Bioactive Natural Products, Department of Biochemistry, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, Minas Gerais CEP 36036-900, Brazil.
Thayná G FerreiraLaboratory of Bioactive Natural Products, Department of Biochemistry, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, Minas Gerais CEP 36036-900, Brazil.
Ari S de O LemosLaboratory of Bioactive Natural Products, Department of Biochemistry, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, Minas Gerais CEP 36036-900, Brazil.
Thalita de F SouzaLaboratory of Bioactive Natural Products, Department of Biochemistry, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, Minas Gerais CEP 36036-900, Brazil.
Lara M CamposLaboratory of Bioactive Natural Products, Department of Biochemistry, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, Minas Gerais CEP 36036-900, Brazil.
Priscila de L PaulaLaboratory of Bioactive Natural Products, Department of Biochemistry, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, Minas Gerais CEP 36036-900, Brazil.
Nubia B AndradeLaboratory of Bioactive Natural Products, Department of Biochemistry, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, Minas Gerais CEP 36036-900, Brazil.
Lívia R GamaranoLaboratory of Bioactive Natural Products, Department of Biochemistry, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, Minas Gerais CEP 36036-900, Brazil.
Lucas S QueirozResearch Group for Food Production Engineering, National Food Institute, Technical University of Denmark, Ørsteds Plads, Kongens Lyngby 2800, Denmark.
Bruno de A OliveiraDepartment of Chemistry, Institute of Exact Sciences, Federal University of Juiz de Fora, Juiz de Fora, Minas Gerais CEP 36036-900, Brazil.
Adilson D da SilvaDepartment of Chemistry, Institute of Exact Sciences, Federal University of Juiz de Fora, Juiz de Fora, Minas Gerais CEP 36036-900, Brazil.
Luciana M ChedierDepartment of Botany, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, Minas Gerais CEP 36036-900, Brazil.
Ângelo M L DenadaiDepartment of Pharmacy, Institute of Life Sciences, Federal University of Juiz de Fora, Campus Governador Valadares, Juiz de Fora, Minas Gerais CEP 36036-900, Brazil.
Guilherme D TavaresDepartment of Pharmacy, Faculty of Pharmacy, Federal University of Juiz de Fora, Juiz de Fora, Minas Gerais CEP 36036-900, Brazil.
Thaís N BarradasDepartment of Pharmacy, Faculty of Pharmacy, Federal University of Juiz de Fora, Juiz de Fora, Minas Gerais CEP 36036-900, Brazil.
Rodrigo L FabriLaboratory of Bioactive Natural Products, Department of Biochemistry, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, Minas Gerais CEP 36036-900, Brazil.ORCID https://orcid.org/0000-0002-0167-2277

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ursolic acid (UA) is a pentacyclic triterpenoid known for its wide range of biological activities, including anticancer and antimicrobial effects. However, its poor solubility in water limits its therapeutic potential. Therefore, this work aims to evaluate the physicochemical properties of the ursolic acid/β-cyclodextrin inclusion complex (UA/βCD IC) and investigate the enhancement of the

Identifiers

PMID40224443
PMCPMC11983339

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.