Evidence map›Paper›PMID 40224427›Full record

ArticleACS omega2025

Quantum Mechanical Spectral Analysis and Aldose Reductase Inhibition Evaluation of Synthetic New Pyrrolopyrazinones.

Yun-Seo Kil, Junhyeung Park, Byeong-Seon Jeong, Punam Thapa, Young Jun Ok, Hyukjae Choi, Jee-Heon Jeong, Joo-Won Nam

Abstract read
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yun-Seo KilCollege of Pharmacy, Yeungnam University, Gyeongsan, Gyeongbuk 38541, South Korea.
Junhyeung ParkDepartment of Precision Medicine, School of Medicine, Sungkyunkwan University, Suwon, Gyeonggi 16419, South Korea.
Byeong-Seon JeongCollege of Pharmacy, Yeungnam University, Gyeongsan, Gyeongbuk 38541, South Korea.ORCID https://orcid.org/0000-0002-7814-6638
Punam ThapaCollege of Pharmacy, Yeungnam University, Gyeongsan, Gyeongbuk 38541, South Korea.
Young Jun OkCore Research Support Center for Natural Products and Medical Materials, Yeungnam University, Gyeongsan, Gyeongbuk 38541, South Korea.
Hyukjae ChoiCollege of Pharmacy, Yeungnam University, Gyeongsan, Gyeongbuk 38541, South Korea.
Jee-Heon JeongDepartment of Precision Medicine, School of Medicine, Sungkyunkwan University, Suwon, Gyeonggi 16419, South Korea.
Joo-Won NamCollege of Pharmacy, Yeungnam University, Gyeongsan, Gyeongbuk 38541, South Korea.ORCID https://orcid.org/0000-0001-5502-0736

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Maillard reaction, known as the condensation of reduced sugars with amino acids, can be a great source of pyrroles for the discovery of bioactive compounds. In the present study, using glucose and l-alanine, two new pyrrolopyrazinones (

Identifiers

PMID40224427
PMCPMC11983166

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.