Evidence map›Paper›PMID 40224414›Full record

ArticleACS omega2025

Decoding Specificity of Cyanobacterial MysDs in Mycosporine-like Amino Acid Biosynthesis through Heterologous Expression in

Xiaoyou Zheng, Peifeng Xie, Andrew Chen Cai, Yuze Jiang, Sirui Huang, Xiaochong Ma, Honghao Su, Boxiang Wang

Abstract read
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiaoyou ZhengChurchill College, University of Cambridge, Storey's Way, Cambridge CB3 0DS, U.K.
Peifeng XieLINK SPIDER Co., Ltd., 11 Langshan Rd, Nanshan District, Shenzhen 518000, China.
Andrew Chen CaiLINK SPIDER Co., Ltd., 11 Langshan Rd, Nanshan District, Shenzhen 518000, China.
Yuze JiangLINK SPIDER Co., Ltd., 11 Langshan Rd, Nanshan District, Shenzhen 518000, China.
Sirui HuangThurgood Marshall College, University of California, 9500 Gilman Dr., La Jolla, San Diego, California 92093, United States.
Xiaochong MaLINK SPIDER Co., Ltd., 11 Langshan Rd, Nanshan District, Shenzhen 518000, China.
Honghao SuEarlham Institute, Norwich Research Park, Norwich NR4 7UZ, U.K.ORCID https://orcid.org/0009-0002-8382-7654
Boxiang WangLINK SPIDER Co., Ltd., 11 Langshan Rd, Nanshan District, Shenzhen 518000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mycosporine-like amino acids (MAAs) are potent natural UV-protectants, but their industrial production is hindered by efficiency and sustainability issues in large-scale extraction of native hosts. Heterologous biosynthesis in chassis organisms provides a promising alternative route, although the substrate promiscuity of the ATP-grasp ligase MysD complicates the biosynthesis of specific MAAs. In this study, we developed a

Identifiers

PMID40224414
PMCPMC11983340

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.